SKL426

SKL426 - Names and Identifiers

Name	7-chlorothiazolo[5,4-d]pyrimidine
Synonyms	SKL426 7-chlorothiazolo[5,4-d]pyrimidine 7-Chlorothiazole[5,4-d]pyrimidine thiazolo[5,4-d]pyrimidine, 7-chloro- Thiazolo[5,4-d]pyriMidine, 7-chloro- 7-Chloro[1,3]thiazolo[5,4-d]pyrimidine 7-chloro-[1,3]thiazolo[5,4-d]pyrimidine
CAS	13316-12-6
InChI	InChI=1/C5H2ClN3S/c6-4-3-5(8-1-7-4)10-2-9-3/h1-2H

SKL426 - Physico-chemical Properties

Molecular Formula	C5H2ClN3S
Molar Mass	171.61
Density	1.639
Melting Point	152-154℃
Boling Point	295℃
Flash Point	132℃
Vapor Presure	0.00274mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.727

SKL426 - Introduction

7-Chlorothiazolo [5,4-D] pyrimidine is an organic compound containing thiazole and pyrimidine rings in its structure. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: 7-Chlorothiazolo [5,4-D] pyrimidine is a white to light yellow crystalline solid.
-Melting point: about 225-228 ℃.
-Solubility: Soluble in DMSO (dimethyl sulfoxide) and chloroform, insoluble in water.

Use:
-7-Chlorothiazolo [5,4-D] pyrimidine is a synthetic intermediate with wide applications in the field of medicine and pesticide.
-In the field of medicine, it is used to synthesize certain anti-cancer drugs (such as cisplatin) and antiviral drugs (such as teribavir), as well as intermediates for some other drugs.
-In the field of pesticides, it is used for synthetic pesticides and fungicides.

Preparation Method:
- 7-chlorothiazolo [5,4-D] pyrimidine has many preparation methods, one of which is commonly used to obtain the compound by hydrogenation of 4-(7-chloro -1H-thiazolo [5,4-D] pyrimidine -4-yl) benzyl -1-cyanopyrimidine.

Safety Information:
-The safety of 7-chlorothiazolo [5,4-D] pyrimidine is application-specific and should be carefully followed.
-The compound may cause irritation to the eyes, skin and respiratory tract. After contact, rinse with water in time and avoid inhaling dust.
-in storage and handling, should be away from the fire and oxidant, to avoid contact with strong acid, alkali and other substances.
-In case of discomfort or accident, seek medical attention immediately and bring the relevant safety data and label of the compound.

Last Update：2024-04-09 20:49:11