SM164
SM-164
CAS: 957135-43-2
Molecular Formula: C62H84N14O6
SM164 - Names and Identifiers
| Name | SM-164 |
| Synonyms | SM164 SM 164 SM-164 SM164 SM 164 (pharmaceutical) (3S,3'S,6S,6'S,10aS,10'aS)-N,N'-[1,4-Phenylenebis[4,1-butanediyl-1H-1,2,3-triazole-1,4-diyl[(S)-phenylmethylene]]]bis[decahydro-6-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-5-oxo-pyrrolo[1,2-a]azocine-3-carboxamide Pyrrolo[1,2-a]azocine-3-carboxamide, N,N'-[1,4-phenylenebis[4,1-butanediyl-1H-1,2,3-triazole-1,4-diyl[(S)-phenylmethylene]]]bis[decahydro-6-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-5-oxo-, (3S,3'S,6S,6'S,10aS,10'aS)- (S,3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-(1,1'-(4,4'-(1,4-phenylene)bis(butane-4,1-diyl))bis(1H-1,2,3-triazole-4,1-diyl))bis(phenylmethylene))bis(6-((S)-2-(2-methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide) |
| CAS | 957135-43-2 |
SM164 - Physico-chemical Properties
| Molecular Formula | C62H84N14O6 |
| Molar Mass | 1121.45 |
| Density | 1.33±0.1 g/cm3(Predicted) |
| Solubility | 10 mM in DMSO |
| Appearance | solid |
| Color | White to pale-yellow |
| pKa | 12.62±0.40(Predicted) |
| Storage Condition | -20°C |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
SM164 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 0.892 ml | 4.459 ml | 8.917 ml |
| 5 mM | 0.178 ml | 0.892 ml | 1.783 ml |
| 10 mM | 0.089 ml | 0.446 ml | 0.892 ml |
| 5 mM | 0.018 ml | 0.089 ml | 0.178 ml |
Last Update：2024-01-02 23:10:35
SM164 - Reference Information
| biological activity | SM-164 is a potent, non-peptide, cell-permeable XIAP antagonist, targeting the BIR2 and BIR3 domains has an IC50 value of 1.39 nM. SM-164 can induce apoptosis and tumor regression. |
| Target | TargetValue XIAP (Cell-free assay) 1.39 nM |
| Target | Value |
| XIAP (Cell-free assay) | 1.39 nM |
Last Update：2024-04-10 22:29:15
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Spot supply
Product Name: SM-164 Visit Supplier Webpage Request for quotationCAS: 957135-43-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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