SODIUM-L-2-HYDROXY-PROPIONATE
dl-lactic acid sodium salt
CAS: 312-85-6;72-17-3
Molecular Formula: C3H5NaO3
SODIUM-L-2-HYDROXY-PROPIONATE - Names and Identifiers
| Name | dl-lactic acid sodium salt |
| Synonyms | PURASAL(R)S Sodium lactate SODIUM L-LACTATE dl-lactic acid sodium SODIUM L-LACTATE SOLUTION dl-lactic acid sodium salt sodium 2-hydroxypropanoate Sodium DL-lactate solution SARCOLACTIC ACID SODIUM SALT SODIUM-L-2-HYDROXY-PROPIONATE dl-lactic acid sodium salt solution |
| CAS | 312-85-6 72-17-3 |
| EINECS | 206-231-5 |
| InChI | InChI=1/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1 |
SODIUM-L-2-HYDROXY-PROPIONATE - Physico-chemical Properties
| Molecular Formula | C3H5NaO3 |
| Molar Mass | 112.06 |
| Density | 1.33 |
| Melting Point | 163-165°C(lit.) |
| Solubility | It is miscible with water and alcohol, and its aqueous solution is neutral |
| Appearance | Colorless liquid |
| Color | 50 APHA max. |
| PH | 7.48(1 mM solution);7.85(10 mM solution);8.3(100 mM solution);8.61(1000 mM solution) |
| Storage Condition | 2-8°C |
| Stability | Stable. |
| Sensitive | Easily absorbing moisture |
| Refractive Index | 1.422-1.425 |
| MDL | MFCD00065400 |
| Physical and Chemical Properties | A colorless or nearly colorless syrup-like liquid. Melting point of 17 degrees C, boiling point of 140 degrees C (decomposition). It is miscible with water and alcohol, and its aqueous solution is neutral. No odor, easy to absorb moisture. |
SODIUM-L-2-HYDROXY-PROPIONATE - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 1 |
| RTECS | OD5680000 |
| FLUKA BRAND F CODES | 3-10 |
SODIUM-L-2-HYDROXY-PROPIONATE - Nature
Open Data Verified Data
colorless or yellowish transparent syrup-like liquid, slightly salty and bitter. Miscible in water, ethanol and glycerol. Has a strong ability to absorb water.
Last Update：2024-01-02 23:10:35
SODIUM-L-2-HYDROXY-PROPIONATE - Preparation Method
Open Data Verified Data
sodium hydroxide is added to lactic acid for neutralization, and after concentration, neutralization and dilution with alkali are performed to obtain a finished product.
Last Update：2022-01-01 10:09:16
SODIUM-L-2-HYDROXY-PROPIONATE - Standard
Authoritative Data Verified Data
This product contains sodium lactate (C3H5Na03) not less than 40.0%(g/g).
Last Update：2024-01-02 23:10:35
SODIUM-L-2-HYDROXY-PROPIONATE - Trait
Authoritative Data Verified Data
- This product is colorless or almost colorless clear viscous liquid.
- This product can be mixed with water, ethanol or glycerin.
Last Update：2022-01-01 13:37:01
SODIUM-L-2-HYDROXY-PROPIONATE - Use
Open Data Verified Data
used as emulsifier, humectant, flavor improver, quality improver, antioxidant synergist and pH regulator. It can also be used instead of sodium benzoate as a preservative in the food industry. The dosage was added as needed for normal production.
Last Update：2022-01-01 10:09:17
SODIUM-L-2-HYDROXY-PROPIONATE - Differential diagnosis
Authoritative Data Verified Data
This product is sodium salt and lactate identification reaction (General 0301).
Last Update：2022-01-01 13:37:02
SODIUM-L-2-HYDROXY-PROPIONATE - Exam
Authoritative Data Verified Data
pH
take this product, add water to make a solution containing 0.112g of sodium lactate per lml, heat it in a water bath for 30 minutes, let it cool, and measure it according to law (General rule 0631). The pH value should be 6.5~7.5.
clarity and color of solution
This product should be clear and colorless, such as color, and yellow 1 Standard Colorimetric liquid (General Principles 0901 The first method) comparison, not deeper.
chloride
take l.Og of this product and check it according to law (General rule 0801). Compared with the control solution made of 5.0 ml of standard sodium chloride solution, it should not be more concentrated (0.005%).
sulfate
take 2.0g of this product and check it according to law (General rule 0802). Compared with the control solution made of 0.010% of standard potassium sulfate solution, it should not be more concentrated ().
Carmine, oxalate, phosphate or tartrate
take l.Og of this product, make 5ml with appropriate amount of water, mix well, add 1ml of calcium chloride test solution, heat in water bath for 5 minutes, and do not produce turbidity.
methanol and methyl ester
Take 40g of this product, precision weighing, set the Kjeldahl Flask, add 10ml of water, carefully add 30ml of 5mol/L potassium hydroxide solution, water vapor distillation, add 10ml of ethanol to a 100ml measuring flask as an absorption solution, collect the distillate to about 95ml, dilute to the scale with water, and shake to obtain a test solution. Another 10 mg of methanol was weighed accurately, and the mixture was placed in a 10% measuring flask, diluted to the scale with ethanol solution, and then shaken to form a reference solution. Take 10ml of the reference solution and 10ml of the test solution respectively, put them in 25ml measuring flask, and add potassium permanganate-phosphoric acid solution (take 3g of potassium permanganate, add 15ml of phosphoric acid and 70ml of water for dissolution, dilute to 100ml with water, then obtain) 5ml, mix well, stand for 15 minutes, add each oxalic acid-sulfuric acid solution (take 50ml of water, carefully add 50ml of sulfuric acid, mix well, cool down, add 5g of oxalic acid, dissolve, (2ml), stirred with a glass rod until the solution was colorless, added with 5ml of magenta sulfite solution, diluted with water to scale, shaken, and left to stand for 2 hours. The absorbance was measured at a wavelength of 0401 nm by ultraviolet-visible spectrophotometry (general rule) with water as a blank. The absorbance of the test solution shall not be greater than that of the reference solution (0.025%).
reducing sugar
take 0.5g of this product, Add 10ml of water, add 6mL of Alkaline copper tartrate test solution, heat and boil for 2 minutes, and no red precipitate will be generated.
Heavy metals
take an appropriate amount of this product (about 2.0g of sodium lactate), put it in a quartz crucible (or europium crucible), and check it according to law (General Principles 0821, second method), heavy metals should not be more than 10 parts per million.
arsenic salt
take an appropriate amount of this product (about equivalent to sodium lactate l.Og), add hydrochloric acid 5ml and water 23ML, according to the law inspection (General Principles 0822 The first law), should comply with the provisions (0.0002%).
Last Update：2022-01-01 13:37:02
SODIUM-L-2-HYDROXY-PROPIONATE - Content determination
Authoritative Data Verified Data
take about 0.2g of this product, accurately weigh it, put it in an Erlenmeyer flask, dry it at 105°C for 1 hour, add 15ml of glacial acetic acid and 2ml of acetic anhydride, heat it to dissolve it, and let it cool, add 1 drop of crystal violet indicator solution and use perchloric acid titration solution (0.1 mol/L titration to solution blue-green, and the results of the titration with blank test correction. Each 1 ml of perchloric acid titration solution (0.1 mol/L) corresponds to 11.21mg of C3H5Na03.
Last Update：2022-01-01 13:37:03
SODIUM-L-2-HYDROXY-PROPIONATE - Category
Authoritative Data Verified Data
alkaline sodium salt.
Last Update：2022-01-01 13:37:04
SODIUM-L-2-HYDROXY-PROPIONATE - Storage
Authoritative Data Verified Data
light shielding, sealed storage.
Last Update：2022-01-01 13:37:04
SODIUM-L-2-HYDROXY-PROPIONATE - Sodium lactate injection
Authoritative Data Verified Data
This product is a sterile aqueous solution of sodium lactate. The C3H5Na03 content shall be between 95.0% and 110.0% of the labeled amount.
trait
This product is a clear colorless liquid.
identification
This product is sodium salt and lactate identification reaction (General 0301).
examination
- pH value should be 6.0~7.5 (General 0631),
- bacterial endotoxin this product, according to the law to check (General 1143), the amount of endotoxin per lml should be less than 1.0EU.
- others should comply with the relevant provisions under injection (General 0102).
Content determination
take 1 ml of this product and put it in an Erlenmeyer flask, dry it at 105°C for 1 hour, and start from "add 15ml of glacial acetic acid and 2ml of acetic anhydride" according to the method under the item of sodium lactate solution content determination, determination according to law. Each l of perchloric acid titration solution (0.1 mol/L) corresponds to 11.21mg of C3H5Na03.
category
Same as sodium lactate solution.
specification
(l)10ml:1.12g (2 )20ml:2.24g (3)50ml:5.60g
storage
shading, sealed storage.
Last Update：2022-01-01 13:37:04
SODIUM-L-2-HYDROXY-PROPIONATE - Sodium Lactate Ringer’s Injection
Authoritative Data Verified Data
This product is a sterile aqueous solution of sodium lactate, sodium chloride, potassium chloride and calcium chloride, containing sodium lactate (C3H5Na03) should be 93.0% ~ 107.0% of the label amount; Containing sodium chloride (NaCl), potassium chloride (KCl), calcium chloride (CaCl2 · 2H20)) should be between 95.0% and 105.0% of the label amount.
trait
This product is a clear colorless liquid.
identification
This product is calcium salt identification (2) reaction, sodium salt identification (1) reaction, potassium salt, lactate and gasification identification (1) reaction (General 0301).
examination
- the pH value should be 6.0 to 7.5 (General 0631).
- total chlorine precision measure 10ml of this product, add 10ml of glacial acetic acid, 75ml of methanol and 3 drops of eosin sodium indicator solution, and titrate to pink with silver nitrate titration solution (0.lmol/L). Each 1 ml of silver nitrate titration solution (0.1 mol/L) corresponds to 3.545mg of C1. This product should contain 3.60~4.15mg of total chlorine per lml.
- Precious Metal: take 100ml of this product, evaporate to about 20ml on a water bath, let it cool, add 2ml of acetate buffer (pH 3.5), and make 25ml with appropriate amount of water, inspection according to law (General Principles 0821, Law 1), containing heavy metals must not exceed three million.
- osmolality the osmolality shall be 0632-240 m0smol/kg for inspection according to law (General rule 270).
- arsenic salt take this product 25ml, add hydrochloric acid 5ml, inspection according to law (General Principles 0822 The first law), should comply with the provisions (0.000008%).
- the bacterial endotoxin should be taken from this product and checked according to law (General rule 1143). The amount of endotoxin in Sodium Lactate Ringer’s Injection should be less than 0.50EU per lml.
- others should comply with the relevant provisions under injection (General 0102).
Content determination
- potassium chloride a solution containing 15ug of potassium chloride per 1 ml was prepared as a reference solution by taking vaporized potassium dried to constant weight at 105 ° C., weighing it precisely, dissolving it with water, and quantitatively diluting it.
- take 10ml of this product with precision, put it in a 100ml measuring flask, dilute it to scale with water, shake it well, take 10ml with precision, put it in a 100ml measuring flask, dilute it to scale with water, shake it well, as a test solution.
- determination precision: take 15ml, 20ml and 25ml of the reference solution, respectively put it in a 100ml measuring flask, and add mixed solution (sodium lactate 0.31g, sodium chloride 0.60g, calcium chloride (CaCl2 • 2H20 )0.02g, put in a measuring flask, add water to dissolve and dilute to the scale, shake] 1.0, dilute to the scale with water, shake. Each of the above solutions and the test solution were measured at a wavelength of 0406 Mn by atomic absorption spectrophotometry (the first method of general rule) and calculated.
- sodium chloride sodium chloride dried to constant weight at 105 ° C. Was accurately weighed, dissolved with water and quantitatively diluted to prepare a solution containing 20% of sodium chloride per 1 ml, and was shaken to be used as a reference solution.
- take 2ml of this product with precision, put it in a 100ml measuring flask, dilute it to the scale with water, shake it well, take 2ml with precision, put it in a 100ml measuring flask, dilute it to the scale with water, shake it well, as a test solution.
- measurement precision: 10ml, 15ml and 20ml of the reference solution were respectively placed in a 100ml measuring flask, diluted with water to scale, and shaken. Each of the above-mentioned solutions and the test solution were measured at a wavelength of 0406 nm by atomic absorption spectrophotometry (the first method in general).
- calcium chloride, about 105g of calcium carbonate dried to constant weight at 0.3125°C, is accurately weighed, placed in a 500ml measuring flask, dissolved with 1 mol/L hydrochloric acid solution (25ml), diluted with water to the mark, A solution containing 250ug of calcium in each solution was prepared and shaken as a control solution. Preparation of lanthanum solution weigh 6.6g of lanthanum oxide, Add 10ml of hydrochloric acid to dissolve, dilute to ML with water, and shake.
- take 10ml of this product, put it in a 50ml measuring flask, add 2ml of lanthanum solution, dilute it with water to the scale, shake it well, and use it as a test solution.
- The standard solution (1 ml, 2ml and 3ml) was measured and placed in 50ml measuring flask respectively. Sodium lactate (0.31g), sodium chloride (0.60g) and potassium chloride (0.03g) were added into the mixed solution respectively, add 100ml measuring flask, add water to dissolve and dilute to the scale, shake 10ml and lanthanum solution 2ml, dilute to the scale with water, shake well. Each of the above solutions and the test solution were taken, measured at a wavelength of 422.7nm by atomic absorption spectrophotometry (the first method of general rule 0406), and calculated.
- sodium lactate precision take 10ml of this product, put it in an iodine flask, Precision Add 25ml of potassium dichromate titration solution (0.016 67mol/L), add 15ml of sulfuric acid (l-2), heat it on a water bath for 20 minutes, cool, add potassium iodide 2.5g, plug, add a little water to the mouth of the bottle, place in the dark for 10 minutes, add 10ml of water, use sodium thiosulfate titration solution (0.lmol/L) titration to the near end point, add lml of starch indicator solution, continue titration to blue disappeared, the solution is bright green, and the titration result is corrected by blank test. Each 1 ml of potassium dichromate titration solution (0.01667mol/L) corresponds to 2.802mg of C3H5Na03.
category
humoral, electrolyte, acid-base balance regulator.
specification
(l)250ml (2)500ml (3)1000ml
storage
sealed storage.
Last Update：2022-01-01 13:37:06
SODIUM-L-2-HYDROXY-PROPIONATE - Reference Information
| EPA chemical information | Information provided by: iaspub.epa.gov (external link) |
| food additive | sodium lactate is made of pure natural high-quality lactic acid and sodium hydroxide. it is colorless or yellowish syrup-like liquid, miscible with water and hygroscopic. 1. Sodium lactate has the following characteristics: (1) reduces water activity. (2) It has the function of water retention, controls the effluent and increases the yield. (3) In frozen meat products, fat oxidation is effectively inhibited. (4) through the interaction with protein, keep protein moisture, increase protein flexibility, make protein tissue expansion, prevent product aging. (5) Sodium lactate is a strong base and weak acid salt, which has a good buffering effect and can effectively adjust the pH value of the product. (6) The US Food and Drug Administration considers "safe and non-toxic substances" (GRAS). 2. Moisturizing properties of sodium lactate Sodium lactate has a strong moisturizing and prevent water loss effect. Compared with other moisturizers, it is less affected by humidity changes and can also play a high-efficiency moisturizing effect under low temperature and dry conditions. 3. Sodium lactate can inhibit the growth of microorganisms Sodium lactate can ingest a large amount of free water in food, effectively reduce the water activity in food, inhibit the growth and reproduction of microorganisms, and prolong the shelf life of food. |
| prescription application | is suitable for correcting metabolic acidosis. Used as a buffer in peritoneal dialysis fluid. It is used for hyperkalemia with severe arrhythmia and QRS wave widening. Used to alkalize urine, prevent and treat uric acid stones, baby enteritis, etc. Intravenous drip: metabolic acidosis: the dosage should be calculated according to the patient's alkali deficiency. the volume (mL) of sodium lactate (mol/L) required = alkali deficiency (mmol/L)× 0.3 × body weight (kg). At present, this drug is not often used to correct metabolic acidosis. Hyperkalemia: 40~60mL of 11.2% injection of this drug can be given intravenously for the first time, and then administered as appropriate. Patients with severe hyperkalemia should be administered under ECG monitoring, and sometimes the dosage needs to be as high as 200mL to be effective. Attention should be paid to monitoring to prevent hypersodium and heart failure. |
| properties | sodium lactate is colorless or yellowish transparent slurry liquid, with strong water absorption ability, odorless or slightly special smell, slightly salty and bitter taste. Miscible with water, ethanol and glycerol, the general concentration is 60 ~ 80%. |
| Use | Sodium lactate is a new type of antiseptic and preservative. It is mainly used in meat and poultry products and has a strong inhibitory effect on meat bacteria. For example, Escherichia coli, Botox, Listeria monocytogenes, etc., through the inhibition of pathogenic bacteria in food, thereby enhancing the safety of food, enhancing and improving the flavor of meat, extend shelf life. Sodium lactate has good dispersibility in raw meat, and has good adsorption to water, so as to effectively prevent dehydration of raw meat, and achieve the effect of preservation and moisture preservation. In addition, sodium lactate also has a fresh-keeping effect on flour products. As a medicine, it is used to relieve acidosis caused by diarrhea, dehydration, diabetes, nephritis and other diseases. It is also used as a condiment, a plasticizer for casein plastics, an antifreeze, a humectant, a substitute for glycerin, and an anti-corrosion agent for alcohol antifreeze. |
| production method | dissolve sodium carbonate (or sodium hydroxide) in water, slowly add lactic acid, heat until boiling to make carbon dioxide escape, adjust pH to 7, add activated carbon to decolorize, filter, and concentrate the filtrate to 25 ℃ to obtain sodium lactate. |
Last Update：2024-04-09 20:44:15
Supplier List
Spot supply
Product Name: dl-lactic acid sodium salt Request for quotationCAS: 72-17-3
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Product Name: dl-lactic acid sodium salt Request for quotation
CAS: 72-17-3
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 72-17-3
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Product Name: dl-lactic acid sodium salt Request for quotation
CAS: 72-17-3
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 72-17-3
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Spot supply
Product Name: dl-lactic acid sodium salt Request for quotationCAS: 312-85-6;72-17-3
Tel: 86+027-83389957
Email: 1024042217@qq.com
Mobile: 86+18627766980
QQ: 1024042217
Wechat: 18627766980
Product Name: Sodium DL-lactate Visit Supplier Webpage Request for quotation
CAS: 72-17-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 72-17-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: dl-lactic acid sodium salt Request for quotationCAS: 72-17-3
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Product Name: dl-lactic acid sodium salt Request for quotation
CAS: 72-17-3
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 72-17-3
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Product Name: dl-lactic acid sodium salt Request for quotation
CAS: 72-17-3
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 72-17-3
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Spot supply
Product Name: dl-lactic acid sodium salt Request for quotationCAS: 312-85-6;72-17-3
Tel: 86+027-83389957
Email: 1024042217@qq.com
Mobile: 86+18627766980
QQ: 1024042217
Wechat: 18627766980
Product Name: Sodium DL-lactate Visit Supplier Webpage Request for quotation
CAS: 72-17-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 72-17-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History