Saffron-bitter
Picrocrocine
CAS: 138-55-6
Molecular Formula: C16H26O7
Saffron-bitter - Names and Identifiers
Saffron-bitter - Physico-chemical Properties
| Molecular Formula | C16H26O7 |
| Molar Mass | 330.37 |
| Density | 1.31±0.1 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 196℃ (ethyl acetate ) |
| Boling Point | 520.4±50.0 °C(Predicted) |
| Specific Rotation(α) | D20 -58° (c = 0.6) |
| Solubility | Sparingly soluble (24 g/L) (25 °C) |
| Appearance | White crystal or powder |
| pKa | 12.91±0.70(Predicted) |
| Storage Condition | 2-8℃ |
| In vitro study | Picrocrocin exerted growth inhibitory effects on the SK-MEL-2 melanoma cells. The IC 50 of picrocrocin against the SK-MEL-2 cells was 20 μM at 24-h incubation. The antiproliferative activity of picrocrocin was due to apoptosis and cell cycle arrest. In addition, picrocrocin enhanced the ROS levels and decreased the MMP levels of SK-MEL-2 cells. Finally, picrocrocin inhibited the JAK/STAT5 signalling pathway in the SK-MEL-2 melanoma cells. |
Saffron-bitter - Reference Information
| biological activity | Picrocrocin, a carotenoid found in broccoli flowers. Picrocrocin has anti-cancer effects. Picrocrocin inhibited the growth of SKMEL-2 human malignant melanoma cells. |
Last Update：2024-04-09 19:05:16
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Product Name: Picrocrocine Visit Supplier Webpage Request for quotationCAS: 138-55-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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