Sarafloxacinbase
Sarafloxacin
CAS: 98105-99-8
Molecular Formula: C20H17F2N3O3
Sarafloxacinbase - Names and Identifiers
| Name | Sarafloxacin |
| Synonyms | A-56620 98105-99-8 SARAFLOZACIN Sarafloxacin Sarafloxacinbase 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-piperazino-3-quinolinecarboxylic acid 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid 3-quinolinecarboxylic acid, 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)- 1,4-Dihydro-6-fluoro-7-(piperazine-1-yl)-1-(4-fluorophenyl)-4-oxoquinoline-3-carboxylic acid |
| CAS | 98105-99-8 |
| EINECS | 1806241-263-5 |
| InChI | InChI=1/C20H17F2N3O3/c21-12-1-3-13(4-2-12)25-11-15(20(27)28)19(26)14-9-16(22)18(10-17(14)25)24-7-5-23-6-8-24/h1-4,9-11,23H,5-8H2,(H,27,28) |
Sarafloxacinbase - Physico-chemical Properties
| Molecular Formula | C20H17F2N3O3 |
| Molar Mass | 385.36 |
| Density | 1.436±0.06 g/cm3(Predicted) |
| Melting Point | 282-285 °C(Solv: chloroform (67-66-3); ethanol (64-17-5)) |
| Boling Point | 621.4±55.0 °C(Predicted) |
| Flash Point | 329.6°C |
| Solubility | Slightly soluble in sodium hydroxide solution, slightly soluble in methanol. |
| Vapor Presure | 2.67E-16mmHg at 25°C |
| Appearance | White or yellowish crystalline powder |
| Color | Off-White to Pale Beige |
| pKa | 6.17±0.41(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Stability | Hygroscopic |
| Refractive Index | 1.633 |
| MDL | MFCD00865974 |
| Physical and Chemical Properties | Sarfloxacin hydrochloride (Sarafloxacin Monohydrochloride):C20 H17F2N3O3?HCl. [91296-87-6]. The melting point of monohydrate is> 275 ℃. |
| Use | Broad-spectrum antibacterials |
Sarafloxacinbase - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29339900 |
Sarafloxacinbase - Reference
| Reference Show more | 1. [IF=6.057] Song Hu et al."Reliable performance of aggregation-induced emission nanoparticle-based lateral flow assay for norfloxacin detection in nine types of animal-derived food."Talanta. 2020 Nov;219:121245 2. [IF=2.863] Yu Zhang et al."Antibiotic residues in cattle and sheep meat and human exposure assessment in southern Xinjiang, China."Food Sci Nutr. 2021 Nov;9(11):6152-6161 3. [IF=2.896] Chunhui Lu et al."Rapid quantitative detection of chloramphenicol in three food products by lanthanide-labeled fluorescent-nanoparticle immunochromatographic strips."Analytical Methods. 2022 May;14(17):1705-1714 |
Sarafloxacinbase - Nature
Open Data Verified Data
white or light yellow crystalline powder, odorless, slightly bitter in taste, darkened in light. Melting point> 275 °c. Slightly soluble in sodium hydroxide solution, slightly soluble in methanol.
Last Update：2024-01-02 23:10:35
Sarafloxacinbase - Preparation Method
Open Data Verified Data
condensation of 2,4-= chloro-5-fluoroacetophenone with diethyl carbonate followed by condensation with triethyl orthoformate followed by condensation with p-fluoroaniline. Under the action of sodium hydride, the product is refluxed in ethylene glycol dimethyl ether. The hydrolyzed product was condensed with piperazine to obtain sarafloxacin.
Last Update：2022-01-01 09:08:57
Sarafloxacinbase - Use
Open Data Verified Data
quinolones. Can be used for the prevention and treatment of livestock and poultry colibacillosis, Staphylococcus disease, anaerobic bacteria also have a strong killing effect, can also be used for aquaculture disease prevention and control, such as shrimp Vibrio disease, bighead intestinal sepsis and so on.
Last Update：2022-01-01 09:08:57
Supplier List
Multiple SpecificationsSpot supply
Product Name: Sarafloxacin Visit Supplier Webpage Request for quotationCAS: 98105-99-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Multiple SpecificationsSpot supply
Product Name: Sarafloxacin Visit Supplier Webpage Request for quotationCAS: 98105-99-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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