Secrepan
Secretin
CAS: 1393-25-5;17034-35-4
Molecular Formula: C130H220N44O40
Secrepan - Names and Identifiers
Secrepan - Physico-chemical Properties
| Molecular Formula | C130H220N44O40 |
| Molar Mass | 3039.41 |
| Appearance | powder |
| Storage Condition | −20°C |
| MDL | MFCD00133810 |
| Physical and Chemical Properties | Storage Conditions:? 20℃ WGK Germany:3 |
Secrepan - Risk and Safety
| WGK Germany | 3 |
Secrepan - Nature
Open Data Verified Data
is a digestive tract hormone produced by the duodenum and the upper jejunum, secreted by the S cells, soluble in water, molecular weight 3056. Mainly by the kidney clearance, Half-Life is short, 2. 39min. The main factor promoting the release of secretin is gastric acid, and the pH in the duodenum or jejunum is <4.5.
Stimulates the release of secretin. The secretion of secretin is also increased after a meal. Somatostatin and enkephalin can inhibit the release. This product is a linear 27 peptide. It stimulates pancreatic acinar cells to secrete water and bicarbonate. Alkalization of the duodenum facilitates enzyme reaction, inhibits gastric acid secretion and stimulates insulin secretion; It enhances cholecystokinin (CCK) secretagogue; Inhibits postprandial gastrin secretion, and reduces gastric acid, stimulate the secretion of pepsin, inhibit pentagastrin to stimulate the secretion of human gastric acid; And promote bile excretion; Inhibit the contraction of gastrointestinal smooth muscle, reduce the tension of lower esophageal sphincter, but increase the tension of pyloric sphincter, inhibits gastric emptying, increases the effect of CCK on the contraction of the gallbladder.
Last Update：2024-01-02 23:10:35
Secrepan - Use
Open Data Verified Data
- is used in combination with cholecystokinin for the diagnosis of pancreatic diseases; It is also used to cooperate with pancreatic vascular and retroperitoneal gas injection and other imaging, to increase the clarity of vascular imaging and shorten the time of arterial filling, to aid in the diagnosis of a pancreatic tumor or cyst. In addition, it is also used to treat duodenal ulcer, but the action time is too short, and the dose is large.
- usage and dose of ulcer, 50~100 units per day; Intravenous injection of p-s test, 1 ~ 2u/kg body weight, 5 min after the injection of cholecystokinin. Skin test should be performed before use.
- preparation: 100 units/bottle; 75 clinical units/vial (1 Clinical Unit = 4 units).
Last Update：2022-01-01 11:11:43
Secrepan - Safety
Open Data Verified Data
occasional allergic reaction. High dose visible Diarrhea. Acute pancreatitis, allergic asthma and allergic history of patients with caution.
Last Update：2022-01-01 11:11:43
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CAS: 17034-35-4
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Product Name: Secretin porcine Visit Supplier Webpage Request for quotation
CAS: 17034-35-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 17034-35-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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