Molecular Formula | C12H8O4 |
Molar Mass | 216.19 |
Density | 1.368±0.06 g/cm3(Predicted) |
Melting Point | 189-191 °C |
Boling Point | 413.0±45.0 °C(Predicted) |
Storage Condition | 2-8°C |
Physical and Chemical Properties | White-like needle-like crystals, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Oxtail Monohuo. |
In vitro study | Pretreatment of A549 cells with Sphondin (10-50 μM) concentration-dependently attenuates IL-1β-induced COX-2 protein expression and PGE 2 release. |
biological activity | Sphondin can be isolated from Heracleum laciniatum, it inhibited the increase of COX-2 protein and PGE2 release in A549 cells induced by IL-1β. |
Use | analgesic, anti-inflammatory, anti-allergic, smooth muscle antispasmodic. |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |