Molecular Formula | C15H24O |
Molar Mass | 220.35 |
Density | 1.02±0.1 g/cm3(Predicted) |
Boling Point | 284.7 °C |
Specific Rotation(α) | 56 |
Solubility | Soluble in methanol and benzene, slightly soluble in water and n-hexane |
Appearance | oily |
pKa | 15.10±0.40(Predicted) |
Storage Condition | 2-8℃ |
In vitro study | Spathulenol exhibits a high antioxidant activity s in the DPPH and MDA system, exhibits significant DPPH free radical activity, with IC 50 values of 85.60 μg/mL [1]. |
In vivo study | Spathulenol (oral administration; 300 mg/kg) shows a significant inhibition in the Cg-induced mice paw oedema and pleurisy model. In a spontaneous lipoperoxidation rat brain homogenate model, when incubated in controlled temperature and oxygenation conditions, PG-1 exhibits a high activity with an IC 50 value of 26.13 μg/mL, respectively, which is comparable to a commercial antioxidant BHT (38.41 μg/mL), Thus, PG-1 contributes to a decrease in the generation of MDA, which is a toxic product resulting from the degradation of the cell membrane by lipid peroxidation, causing cell ruptures and mutations [1]. |
Application | eucalyptol is an organic alcohol compound, which is mainly used for content determination and not for other purposes. |
store | keep eucalyptol in a cool, dry place and protected from light. |
note | eucalyptol should be stored at low temperature, and the content will be reduced when exposed to air for a long time. |
biological activity | Spathulenol, isolated from Psidium quinenense Sw, has antioxidant, anti-inflammatory, anti-proliferative and anti-mycobacterial activities. Spathulenol showed high antioxidant activity in the DPPH system with an IC50 of 85.60 μg/mL. |