Swertiamarin
Swertiamarin
CAS: 17388-39-5
Molecular Formula: C16H22O10
Swertiamarin - Names and Identifiers
Swertiamarin - Physico-chemical Properties
| Molecular Formula | C16H22O10 |
| Molar Mass | 374.34 |
| Density | 1.57±0.1 g/cm3(Predicted) |
| Melting Point | 113-114° |
| Boling Point | 649.3±55.0 °C(Predicted) |
| Specific Rotation(α) | D20 -127° (c = 1 in 96% ethanol) |
| Flash Point | 237.7°C |
| Solubility | Easily soluble in methanol, ethanol, slightly soluble in water, insoluble in chloroform, petroleum ether |
| Vapor Presure | 1.32E-19mmHg at 25°C |
| Appearance | White flake crystal |
| Color | White to Yellow to Orange |
| Maximum wavelength(λmax) | ['238nm(MeOH)(lit.)'] |
| Merck | 14,9010 |
| BRN | 55278 |
| pKa | 11.56±0.60(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Sensitive | Sensitive to heat |
| Refractive Index | 1.625 |
| MDL | MFCD07783984 |
| Physical and Chemical Properties | White crystals, soluble in water, methanol, ethanol, almost insoluble in chloroform, ether, petroleum ether, derived from the long stem of the Gentiana (Tibet) when medicine, Swertia, green leaf bile, houttuynia. |
Swertiamarin - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| RTECS | UQ1366700 |
| HS Code | 29389090 |
Swertiamarin - Reference
| Reference Show more | 1. Wu Xinyi, Liu Xiuzhang, Qu Yunhui, et al. Box-Behnken Design-Response Surface Methodology to Optimize the Initial Processing Technology of Gentiana Yunnan [J]. ISTIC PKU CA 2020, Volume 31, Volume 15, Issue 1830-1835, Chinese Pharmacy. 2. Yang Yanmei, Lin Li, Lu Youyuan, Ma Xiaohui, Jin Ling, Zhu Tiantian. Analysis of Commodity Specifications of Wild and Cultivated Gentiana macrophylla Based on Multi-index Components [J]. Chinese Journal of Traditional Chinese Medicine, 2016, 41(05):786-792. 3. Pang Guowei, He Jixiang, Tian Yuan. Preparation of High Purity Swertianin by Ultrasonic Extraction-High Pressure Liquid Chromatography [J]. Shandong Journal of Traditional Chinese Medicine, 202039 Volume 7, 732-737,742 pages, ISTIC, 2020. 4. Han Duo, Zhao Zhilian, Liu Weihong, et al. Accumulation of main active ingredients in leaves of three medicinal plants of the genus Gentiana [J]. Chinese Journal of Pharmaceutical Industry 2016 47(007):865-869. 5. Yang Jianhua, Zhu Dandan, Jiang Xiangying, et al. Simultaneous determination of five active ingredients in Xinjiang Pseudodana by RP-HPLC Method [J]. New Chinese Medicine and Clinical Pharmacological 2015 v.26; no.135 (06):116-119. 6. Wang Linlin, Yin Haibo, Zhang Ziyan, et al. Correlation Analysis of Different Soil Nitrogen Application Rates and Active Components of Gentiana [J]. Journal of Liaoning University of Traditional Chinese Medicine 2017 019(005):72-75. 7. Han Duo, Zhao Zhilian, Liu Weihong, etc. Study on Main Secondary Metabolites and Molecular Differences of Gentiana againa [J]. Chinese Journal of Experimental Presentation, 2016, 022(018):35-39. 8. He Caijing, Wang Jing, Liang Shuai, et al. Discussion on Liver Protection Mechanism of Gentiana macrophylla Based on Network Pharmacology [J]. Chinese Journal of Traditional Chinese Medicine, 2020, v.45(08):79-89. 9. Zhu Dandan, Yang Jianhua, ju Bowei, et al. Comparative Study on Contents of Three Iridol Components in Different Parts of Pseudogentian in Xinjiang [J]. Northwest Journal of Pharmacy, 2018, 033(002):171-174. 10. Xiang Xueying, Yang Jianhua, Hu Junping, et al. Study on Extraction and Purification Technology of Iridol Glycosides from Liver-protecting Active Parts of Pseudogentian in Xinjiang [J]. Northwest Journal of Pharmacy, 2019, 34(02):151-158. 11. Han Duo, Zhao Zhilian, Liu Weihong, et al. Preliminary Discussion on Quality Evaluation of White Medicinal Plants Gentiana [J]. Chinese Medicinal Materials, 2016, 39(011):2549-2553. 12. Jin Lin, Li Haifeng, Liu Weihong, etc. Effects of methyl jasmonate on the contents of four terpenoids in gentian leaves [J]. Chinese Pharmacy, 2019, 030(003):344-348. 13. Lu Youyuan, Zhang Xiaobo, Yang Yanmei, et al. Study on Quality Regionalization of Gentiana Gentiana [J]. Chinese Journal of Traditional Chinese Medicine, 2016, 41(017):3132-3138. 14. Yang Yanmei, ma Xiaohui, Lv Peilin, et al. Comparative Study on Seven Index Components of Gentiana macrophylla in Wild and Cultivated Gentiana macrophylla [J]. Chinese Pharmacy, 2016, 27(19):2618-2621. 15. Luo Linyun, Yang Yanmei, Jin Ling. Comparative Study on the Contents of Seven Index Components of Gentiana macrophylla in Qinghai and Gansu [J]. Chinese Journal of Hospital Pharmacy, 2017, 37(008):717-721. 16. Yang Yanmei, Huang Dedong, Lu Youyuan, et al. Study on UPLC Fingerprint of Gentiana macrophylla [J]. Traditional Chinese Medicine, 2016, 39(008):1734-1737. 17. Wu Xinyi, Liu Xiuyu, Qu Yunhui, Shi Pingping, Yang Yan, Li Zhimin, Tian Hao, Gu Liping. Box-Behnken Design-Response Surface Methodology to Optimize Primary Processing Technology of Gentiana yunnanensis [J]. Chinese pharmacy, 2020,31(15):1830-1835. 18. [IF = 4.06] Jianghua Yang et al."Hepatoprotective effects of Gentianella turkestanerum extracts on acute liver injury induced by carbon tetrachloride in ice." Am J Transl Res. 2017; 9(2): 569-579 19. [IF = 4.225] Huang Xian-ju et al."Veratrilla baillonii Franch Could Alleviate Lipid Accumulation in LO2 Cells by Regulating Oxidative, Inflammatory, and Lipid Metabolic Signaling Pathways." Front Pharmacol. 2020 Sep;0:1511 20. [IF = 2.63] Sun Ke-han et al."Comparative Pharmacokinetics of Seven Major Compounds in Normal and Atherosclerosis Mice after Oral Administration of Simiao Yong'an Decoction." Evidence-based Complementary and Alternative Medicine. 2022;2022:4604601 |
Swertiamarin - Reference Information
| overview | swertia bitter glycoside is an iridoid compound isolated from gentianaceae plant swertia. In the in vivo experiment of rats, it was found that swertialoside can reduce the damage of toxic substances to the liver, and can also prevent liver injury caused by hypoxia in rats. |
| use | used for content determination/identification/pharmacological experiments, etc. Pharmacological effects: It has the effects of clearing away heat and detoxification, promoting gallbladder and strengthening stomach, antispasmodic and analgesic. It has the effects of protecting liver and invigorating stomach. |
Last Update：2024-04-09 20:45:29
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CAS: 17388-39-5
Tel: 17505222756
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Product Name: Swertimarine Request for quotation
CAS: 17388-39-5
Tel: 0714-3999186
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QQ: 2853786052
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CAS: 17388-39-5
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
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