Name | Talc |
Synonyms | mg3 Talc Talc? Talcum Agalite Asbestin Asbestine Snowgoose superfine Talc [JAN] Talc Powder French Chalk TALCUM POWDER Cosmetic Talc oxosilanediol TALCTALCTALCTALC Beaver White 200 Talc (Mg3H2(SiO3)4) Magnesium Silicate Talc talc fine powder extra pure Magnesium silicate (natural) HAICHEN TALC POWDER NO1 AND NO2 Magnesium silicate monohydrate (Talc) TALC POWDER, DAB, PH. EUR., B. P., PH. F RANC. |
CAS | 14807-96-6 |
EINECS | 238-877-9 |
InChI | InChI=1/3Mg.4O2Si.H2O.3O/c;;;4*1-3-2;;;;/h;;;;;;;1H2;;;/r3MgO.4O2Si.H2O/c3*1-2;4*1-3-2;/h;;;;;;;1H2 |
InChIKey | FPAFDBFIGPHWGO-UHFFFAOYSA-N |
Molecular Formula | 3MgO.4O2Si.H2O |
Molar Mass | 379.263 |
Density | 2.7-2.8 |
Melting Point | 800 °C |
Water Solubility | Insoluble in water, cold acids, alkalies. |
Solubility | Practically insoluble in water, in ethanol (96 per cent) and in dilute solutions of acids and alkali hydroxides. |
Appearance | Solid |
Color | White to pale gray |
Exposure Limit | ACGIH: TWA 2 mg/m3NIOSH: IDLH 1000 mg/m3; TWA 2 mg/m3 |
Merck | 14,9037 |
Storage Condition | Sealed in dry,Room Temperature |
MDL | MFCD00792903 |
Physical and Chemical Properties | Monoclinic system, usually in the form of leaf-like, scale-like, granular, fibrous aggregate or dense block. The color is white, light green, light gray, light yellow, light brown. relative density: 2.7-2.8g/cm3 |
Use | Widely used in ceramics, paint, linoleum, paper, textile, rubber, coatings, daily chemical and other industrial sectors Rubber, plastic products, paint, paper making and other fillers, is also the main raw material of talcum powder, prickly heat powder |
Hazard Symbols | Xn - Harmful |
Risk Codes | R20 - Harmful by inhalation R37 - Irritating to the respiratory system |
Safety Description | 36 - Wear suitable protective clothing. |
WGK Germany | - |
RTECS | WW2710000 |
TSCA | Yes |
HS Code | 25262020 |
Toxicity | A finely powdered hydrousmagnesium silicate. It is used in a variety of industrial processesand products, including rubber, paints, lubricants, insulating materials, cosmetics, and toiletries, such as baby and dusting powders.Acute inhalation of large quantities of talc, such as infants aspirating a massive amount of powder, has caused death within hoursbecause of drying of the mucous membranes, clogging of thesmaller airways, pulmonary edema and pneumonia. Chronic inhalation of talc, such as occurs in talc miners, leads to talcosis (apneumoconiosis) involving pulmonary fibrosis and pleural sclerosis. Lymph nodes can also be affected. There are suggestions thattalc can result in cervical or ovarian cancer although evidence forthis is not extensive. Some talc is contaminated with asbestos. |
Raw Materials | Magnesium silicate Calcium carbonate |
white to off-white powder. The main component of talc is hydrous magnesium silicate, and the chemical molecule is Mg3 [S14 010] (OH)2, which belongs to layered silicate mineral in structure. The relative density was 2. 75. Soft and smooth. Ultrafine talc powder maintains the layered structure of natural talc, and the dispersion and whiteness are obviously improved, and the reinforcement is better. Talc has chemical stability, high melting point, large specific heat, thermal conductivity, conductivity, low shrinkage, oil absorption ability, acid and alkali resistance and many other characteristics.
talc ore is sent into a hammer mill for coarse crushing, and the crushed product is sent into a vertical dryer through a bucket elevator and a vibrating feeder for drying. After drying, the product is then crushed in a hammer mill. The milled product enters the pulverizer from the Hopper for pulverization, and the milled material is transported to the jet mill for superfine pulverization to obtain a product with a fineness of 500-5000 mesh.
The line of talc by the selection of net, crushing, flotation, drying. The main component is Mg3Si4010 (OH) 2. This product contains magnesium (Mg) should be 17.0% ~ 19.5%.
used as a plastic filler, improve the processing performance, improve the mechanical strength of the product, heat resistance and tensile strength of the function, used in plastic film can increase the plastic film on the light transmittance of scattered light. Adding talc powder in paint and coating can improve the dispersion, fluidity and gloss, and the coating is resistant to exposure and high temperature, and does not change color under UV irradiation, and can maintain the original gloss and color for a long time, it has good acid and alkali corrosion resistance, good water resistance, strong pollution resistance, aging resistance, wear resistance, steam resistance and chemical stability, and strong flame retardant performance, in addition can be used instead of part of the titanium dioxide. Talc is also used as a textile filler and whitening agent; Pharmaceutical and food carrier, additives.
take lO.Og of this product, add 50ml of water, boil for 30 minutes, always supplement the distilled water, filter, the filtrate should show neutral reaction when it meets litmus test paper.
take about 5g of this product, weigh it accurately, put it in a 100ml beaker, add 50ml of fresh boiling and cooling water, heat and boil it for 30 minutes, then cool it, filter through No. 4 vertical melting crucible dried to constant weight at 105°C, wash the filter residue with 5ml of water, combine the wash with the filtrate, evaporate, dry at 105-C for 1 hour, 5mg(0.1%) was not allowed for residual colitis.
take about lg of this product, weigh it accurately, put it in a 100ml plug Erlenmeyer flask, add 20ml of dilute hydrochloric acid accurately, weigh it, soak it for 15 minutes at 501, let it cool, and then weigh it, make up the lost weight with dilute hydrochloric acid, shake well, filter with medium speed filter paper, take 10ml of continued filtrate in a precise amount, put it in an evaporation dish dried to constant weight at 105°C, add 1 ml of dilute sulfuric acid, and evaporate to dryness, 105°C; Dry to constant weight, residue should not exceed 10mg(2.0%).
take this product, according to X-ray powder diffraction method (General 0451) determination, experimental conditions: CuKa radiation graphite monochromator, pipe pressure 40kV, pipe flow 40mA, continuous scanning mode, 20 scanning range of 10 to 13 ° and 24 ° to 26 °, scan step size of 0.02% per minute at 10.5 ° 0.1 ° 20 characteristic peaks for the amphibole characteristic peaks at 24. 3 ° ± 0.1 ° 20 and 12. 1 ° ± 0. The characteristic peak at 1 degree 20 is the characteristic peak of serpentine. If the characteristic peak of asbestos is detected by X-ray powder diffraction, the sample shall be observed under an optical microscope. If fine needle-like fibers are found, and the ratio of length to diameter is greater than 20 or longer than 5pm, it is determined that the sample contains asbestos; Or it is found that at least two of the following cases can also be determined that the sample contains asbestos: parallel fibers in bundles; Fiber bundles are divergent ends; the fibrous material is thin needle-like; There are agglomerates of individual fibers entangled or the fibrous material is curved and should not be detected.
take about 2g of this product, weigh it accurately, burn to constant weight at 600~700°C, and lose no more than 5.0% of weight.
take about 10g of this product, accurately weigh, put it in an Erlenmeyer flask, add 50ml of 0.5mol/L hydrochloric acid solution, shake well, heat and reflux in a water bath for 30 minutes, and let it cool, filter with medium-speed filter paper, put the filtrate into a 100ml measuring flask, wash the container and filter residue with hot water 30ml in portions, filter, wash and put into the same measuring flask, cool, add water to the scale, shake well, as a stock solution for the test, take 5ml of the precise amount, put it in a 200ml measuring flask, dilute it to the scale with 0.25ml /L hydrochloric acid solution, shake it well, and use it as a test solution; the blank solution was prepared by the same method; The appropriate amount of iron standard solution was accurately measured, and diluted with 0.25mol/L hydrochloric acid solution to prepare a series of reference solution containing 5-10mg of iron per 1 ml of l. Take the blank solution, the test solution and the reference solution, according to Atomic Absorption Spectrophotometry (General rule 0406 first method), at the wavelength of. 3nm measurement, calculation, that is obtained. Iron content should not exceed 0.25%.
take the stock solution of the test sample under the item of iron salt as the test solution; Remove the test sample and prepare the blank solution by the same method; Take the appropriate amount of lead standard solution by precision measurement, diluted with 0.25mol/L hydrochloric acid solution to produce lead content of 0 .5-1.25mg of serial control solution. Take the blank solution, the test solution and the reference solution, according to Atomic Absorption Spectrophotometry (General 0406 first method), at the wavelength of 217.Onm measurement, calculation, that is obtained. Lead should not exceed 0.001%.
take 5ml of the sample stock solution under the item of content determination, put it in a 20ml measuring flask, and use a mixed solution (take 10ml of hydrochloric acid and 10ml of 8.9% lanthanum chloride solution, add water to ML) dilute to the scale, shake, as a test solution; The same method to prepare blank solution; Another precision take the appropriate amount of calcium standard solution, diluted with water to make each lml of calcium lOOHg solution, A series of reference solution containing 1-5ug of calcium per 1 ml was prepared by taking an appropriate amount of precision and diluting with the mixed solution. Take the blank solution, the test solution and the reference solution, according to Atomic Absorption Spectrophotometry (General rule 0406 first method), at the wavelength of 422.7nm measurement, calculation, that is obtained. Calcium should not exceed 0.9%.
take 1ml of the stock solution of the test product under the item of content measurement, put it in a 50ml measuring flask, dilute it to the scale with water, shake it well, and take lml with precision, in a 25ml measuring flask, dilute to the scale with a mixed solution (take 10ml of hydrochloric acid and 10ml of 2.5% cesium chloride solution, add water to ML), shake well, and use it as a test solution; Prepare blank solution by the same method; another precision take the right amount of aluminum standard solution, diluted with water to make each lml containing aluminum l. The solution of Oug is diluted with a mixed solution to prepare a series of reference solution containing 10-50Ng of aluminum per 1ml. Take blank solution, test solution and reference solution, with graphite furnace atomizer, according to Atomic Absorption Spectrophotometry (General rule 0406 first method), at the wavelength of 309.3nm, that's right. Aluminium shall not exceed 2.0%.
take 0822 of the test solution under the item of iron salt, add 5ml of hydrochloric acid and 13ml of water, and check according to law (General Principles 0.0002% first law), and shall comply with the regulations ().
take this product about O.lg, precision weighing, put in Polytetrafluoroethylene container, add hydrochloric acid lml, lead-free nitric acid lml and high gas acid lml, stir and shake, add hydrofluoric acid 7ml, on a heating plate, slowly boil to near dryness (about 0.5), add 5ml of hydrochloric acid to the residue, heat to boiling, cool, transfer to a 50ml measuring flask with water, dilute to scale with water, shake well, as a stock solution for the test article. Precisely take 2ml of the stock solution, put it in a 50ml measuring flask, dilute it to the scale with water, shake it, precisely take 2ml, put it in a 100ml measuring flask, A mixed solution (10ml of hydrochloric acid and 10ml of 8.9% lanthanum chloride solution were taken, and water was added to ML) was diluted to the mark, and the mixture was shaken to obtain a test solution. Take appropriate amount of magnesium standard solution with precision and dilute it with water to make solutions containing 10ug, 15ug, 20ug and 25ug of magnesium per lml respectively, the mixture was diluted to the scale with the mixed solution, and the mixture was shaken as a control solution. Take the blank solution, the test solution and the reference solution, according to Atomic Absorption Spectrophotometry (General rule 0406 first method), measured at the wavelength of. 2NM, calculated by Standard curve method, that is.
pharmaceutical excipients, lubricants, etc.
Store in dry place.
What is talc? | talc is a hydrous layered silicate mineral with the chemical formula 3MgO · 4 SiO2 · H2O. Weak alkaline pH value of 9.0~9.5, with good chemical stability, low hardness, lipophilic and hydrophobic characteristics, is a rare functional filler. Can be widely used in paper, plastic, paint, ceramics, cosmetics, medicine, rubber, agricultural products, fertilizer and other industries. Especially in the plastic modification industry, the cost of the product can be greatly reduced, and the impact toughness of the plastic can be improved. The talc mainly contains magnesium silicate, in which MgO is 31.7%, silica is 63.5%, and water is 4.8%. Usually a part of MgO is replaced by FeO. In addition, it also contains impurities such as alumina. Color rich, white, gray-green, milk white, light red, light blue, light gray, and some pearl or fat luster. In plastic applications, the higher the degree of whiteness, the more popular, after all, high color value. In the crushing, all have to undergo gray to white change, and show different degrees of solid gloss, but after the plastic into the plastic products, there will be a slight change in color. |
talc properties | talc with lubricity, anti-stick, flow aid, fire resistance, acid resistance, insulation, high melting point, chemical inactivity, good hiding power, soft, gloss, adsorption and other excellent physical and chemical properties, due to the crystalline structure of talc is layered, therefore, it has a tendency to easily split into scales and special lubricity. If the content of Fe2O3 is high, its insulation property will be reduced. talc is soft, with Mohs hardness coefficient of 1-1.5, sliding feeling, extremely complete cleavage, easy to crack into thin slices, and small natural rest angle (35 ° ~ 40 °), extremely unstable, the surrounding rock is silicified and talc magnesite, magnesite, lean ore or dolomite marble, with the exception of a small number of moderate stability, generally not stable, joints and fissures are developed, the physical and mechanical properties of ore and surrounding rock have great influence on mining technology. talcum powder in Guangxi: the typical Kanas landform has good transparency of raw ore. High silicon content, good smoothness. Good transparency, mainly used in oil, water-based furniture paint, varnish a class of products. Oil furniture paint requires good transparency, and water-based paint, requires good hiding power, so the choice of Liaoning talc, and latex paint requires good hiding power. Liaoning talc powder: Liaoning talc minerals are fine-grained scale aggregates, which can be enriched into pure talc, or with a small amount of associated minerals such as magnesite, quartz, dolomite, apatite and other components of sliding rock. Pink, white pure talc pure, smooth, whiteness of up to 95 degrees. Good hiding power, mainly used in a class of latex paint. |
Performance | 1. Reinforcing The significant reinforcing effect of reinforced talc on plastic products is mainly due to its unique micro-sheet structure. After processing of talc, the more complete the sheet structure is maintained, the more obvious the enhancement effect is. A larger diameter-to-thickness ratio (the ratio of the average diameter of the flaky particles to its thickness) can improve the rigidity, impact strength, flexural modulus and thermal stability of the plastic article. Such as, the bumper, car interior parts, etc. 2. Insulation and barrier insulation and barrier high-quality ultra-fine talc powder into sheet-like structure, when used in plastic products, can be uniformly layered and dispersed in the resin. Like the metal structure network embedded in cement products, it can form an enhanced support form with excellent mechanical properties while maintaining the advantages of plastic, which can improve the physical properties of plastic products, also has obvious insulation, barrier effect. 3. Nucleation The smooth feeling of talc is very obvious, and the opening property of the plastic with the addition of talc powder is obviously improved, and the anti-adhesion property of the film can be improved. When ultrafine talc (1 μm or less) is uniformly dispersed in the plastic matrix, it can act as a nucleating agent, for example, in PET plastics. 4. Aging resistance talc, mica, kaolin and other silicon-containing (Si) minerals have the barrier properties of infrared and ultraviolet rays, and have obvious effects of heat preservation and aging resistance in plastic products. |
pharmacological effects | protective effects on skin and mucosa due to the small size and large total area of talc, can absorb a large number of chemical irritants or poisons, so when spread on the surface of inflamed or damaged tissue, can have a protective effect; When taken internally, in addition to the protection of the inflamed gastrointestinal mucosa and play the role of anti vomiting, antidiarrheal effect, but also to prevent the absorption of toxins in the gastrointestinal tract. Talc is not completely harmless and can cause granulomas in the abdomen, rectum, vagina, etc. antibacterial activity The culture medium containing 10% talc had inhibitory effect on Salmonella typhi and Salmonella paratyphi; using the rule of paper has only mild bacteriostatic effect on meningococcus. |
application in the plastic industry | the addition of talc can change a variety of properties of plastics, such as molding shrinkage, surface hardness, flexural modulus, tensile strength, impact strength, hot deformation temperature, molding process and product dimensional stability; Ultrafine mesh talc powder added to the plastic, can significantly improve the rigidity and creep resistance of plastic products, hardness and resistance to surface scratch, heat resistance and heat distortion temperature; Considerable fineness of talc can also improve the impact strength of plastic products, and also has a lubricating effect after adding, can play a role in promoting flow, to improve the processing technology of plastics, it also has a significant feature, that is, the role of nucleating agents. talc is commonly used for filling polypropylene. Talcum powder has the characteristics of sheet-like structure in Flake configuration. Thus, talc with a finer particle size can be used as a reinforcing filler for polypropylene. In the modified system of polypropylene, adding ultrafine talc not only can significantly improve the rigidity, surface hardness, thermal creep resistance, electrical insulation, dimensional stability of polypropylene products, it is also possible to increase the impact strength of the polypropylene. Adding a small amount of talc in polypropylene can also play the role of nucleating agent, improve the crystallinity of polypropylene, so as to improve the mechanical properties of polypropylene, and because of the improvement of crystallinity, grain refinement, it can also improve the transparency of polypropylene. Polypropylene Composites filled with 20% and 40% ultrafine mesh talc, both at room temperature and high temperature, can significantly improve the rigidity of polypropylene and creep resistance at high temperature. |
carcinogenicity | The Institute of safety evaluation of China Food and Drug Control Institute has preliminarily sorted out the carcinogenic property of talc according to the "carcinogen list" published by the International Agency for Research on Cancer World Health Organization (WHO) degree: talc without asbestos (asbestos is a Group 1 carcinogen) or asbestos-like fibers: Group 3 carcinogens, possibly carcinogenic to humans, but there are no sufficient human or animal data. talcum powder (perineal use): Category 2B carcinogen, I .e., limited evidence of carcinogenicity in humans, insufficient evidence of carcinogenicity in experimental animals, or insufficient evidence of carcinogenicity in humans, there is sufficient evidence of carcinogenicity in experimental animals. In other words, it is not clear whether talcum powder without asbestos impurity is carcinogenic or not, and there is no sufficient data to show that it is carcinogenic, and it is at a stage where it is suspected to be carcinogenic. The use of talcum powder in the perineum is less likely to cause cancer (but may contact the ovaries via the vaginal route). at present, it is considered that the main carcinogenic exposure routes of talc are pulmonary inhalation and perineal exposure (which may cause cancer in lung and ovary), that is, it is not carcinogenic to the skin (except the perineum). In addition, some people believe that talc contains asbestos impurities, and asbestos is a class 1 carcinogen (the carcinogenic substance is identified), and thus there are concerns about the safety of talc. However, China's 2015 edition of the "safety and technical specifications for cosmetics" clearly stipulates that the detection of asbestos in cosmetics is prohibited, that is, as long as it is a formal legal cosmetics, there will be no asbestos impurities in the product. |
toxicity | FAO/WHO, no special provisions (2001). Actually non-toxic. But can not be inhaled into the lungs, so as not to cause dust Pneumonia. GRAS(FDA,§ 182.70,2000). |
usage limit | GB 2760-2002: preserved fruit, apricot food, 20g/kg. |
maximum allowable use amount of food additives maximum allowable residue standard | The Chinese name of the additive the Chinese name of the additive is allowed to use the food Chinese name of the additive function maximum allowable use amount (g/kg) the maximum allowable residue (g/kg) Talc Powder Gum-based candy gum-based candy base material according to the production needs of the appropriate amount of use (except for special provisions) talcum powder food processing aids for food industry/generally should be made before the final product, with the provisions of the food residues in the exception of talcum powder (Licorice Products) anti-caking agent 20.0 talc cold fruit anti-caking agent 20.0 |
How to detect the content of talc? | the detection method of talcum powder content in food should be in accordance with the national standard GB/T21913-2008 "determination of talcum powder in food. The standard is applicable to the detection of talcum powder in all foods, and the detection limit is 0.15g/100g. The detection steps are as follows: because talc powder is insoluble in mixed acid (nitric acid perchloric acid) and can react with hydrofluoric acid to form water-soluble magnesium salt, the sample containing talc powder can be digested with mixed acid and filtered, other magnesium-containing substances were removed, and then digested with mixed acid and hydrofluoric acid, and then the magnesium content in the test solution was determined by flame atomic absorption spectrometry. Based on the magnesium content, the talc content in the sample was calculated. |
Chemical properties | monoclinic system, usually in the form of leaf-like, scale-like, granular, fibrous aggregate or dense block. The color is white, light green, light gray, light yellow, light brown. |
Use | talc powder modified by natural silicate, after special surface treatment, it is more easily dispersed in the rubber for the physical properties of the reinforcement with special functions, especially compression and touch, will be used in rubber foam products, EPDM, PCV, wire and cable material effect is particularly obvious. It can be widely used in ceramics, paint, linoleum, paper, textile, rubber, coatings, daily chemical industry and many other industrial sectors, can be used as a filler, is also the main raw material of talcum powder, prickly heat powder. GB 2760-96 for processing aids and gum filler, GMP is limited. Japan (1990) regulation of general food residues in the maximum 0.5%. Chewing gum 5%. |
production method | The natural ore is crushed and then boiled with dilute acid to remove limestone and marble, and then washed thoroughly with water and dried. Mainly produced in the United States, France, Canada, Italy and so on. |
(IARC) carcinogen classification | (Vol. 42, Sup 7) 1987, 3 (Vol. 42, Sup 7, 93) 2010, 2B (Vol. 93) 2010 |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
immediate life-and health-threatening concentrations | 1,000 mg/m3 |