Name | TBPB |
Synonyms | TBPB 1-(1′-(2-Methylbenzyl)-1,4′-bipiperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one 1,3-Dihydro-1-[1'-[(2-methylphenyl)methyl][1,4'-bipiperidin]-4-yl]-2H-benzimidazol-2-one 2H-BenziMidazol-2-one, 1,3-dihydro-1-[1'-[(2-Methylphenyl)Methyl][1,4'-bipiperidin]-4-yl]- |
CAS | 634616-95-8 |
Molecular Formula | C25H32N4O |
Molar Mass | 404.55 |
Density | 1.193±0.06 g/cm3(Predicted) |
Solubility | DMSO: soluble5mg/mL (clear solution; warmed) |
Appearance | powder |
Color | white to beige |
pKa | 12.04±0.30(Predicted) |
Storage Condition | 2-8°C |
WGK Germany | 3 |
biological activity | TBPB is an allosteric agonist of M1 mAChR with an EC50 value of 289nM, it regulates the processing of amyloid and has antipsychotic drug activity in mice. |