TMEM16 BLOCKER I

Name	CaCCinh-A01
Synonyms	CACCINH-A01 CaCCinh-A01 TMEM16 BLOCKER I CaCC(inh)-A01, TMEM16 Blocker I. CACC(INH)-A01, TMEM16 BLOCKER I. 6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid 6-(1,1-Dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid Benzo[b]thiophene-3-carboxylic acid, 6-(1,1-dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydro-
CAS	407587-33-1

Molecular Formula	C18H21NO4S
Molar Mass	347.43
Density	1.305±0.06 g/cm3(Predicted)
Boling Point	429.7±45.0 °C(Predicted)
Solubility	Soluble in DMSO
Appearance	powder
Color	white to beige
pKa	4.49±0.40(Predicted)
Storage Condition	2-8°C
Use	CaCCinh-A01 are inhibitors of TMEM16A and calcium-activated chloride channels (CaCC) with IC50 values of 2.1 and 10 μM, respectively.

WGK Germany

Last Update：2024-01-02 23:10:35

biological activity	CaCCinh-A01 (TMEM16 Blocker I) is a TMEM16A Blocker with an IC50 value of 2.1 μm. CaCCinh-A01 is also an inhibitor of calcium-activated chloride channel (CaCC) with an IC50 value of approximately 10 μm.
Target	Value
TMEM16A (Cell-free assay)	2.1 μM
CaCC (Cell-free assay)	10 μM

Last Update：2024-04-09 21:04:16

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CAS: 407587-33-1
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QQ: 3008007409

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TMEM16 BLOCKER I

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