Molecular Formula | C18H24ClN7OS |
Molar Mass | 421.95 |
Density | 1.47±0.1 g/cm3(Predicted) |
Boling Point | 657.5±55.0 °C(Predicted) |
pKa | 9.27±0.40(Predicted) |
Storage Condition | -20℃ |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.37 ml | 11.85 ml | 23.699 ml |
5 mM | 0.474 ml | 2.37 ml | 4.74 ml |
10 mM | 0.237 ml | 1.185 ml | 2.37 ml |
5 mM | 0.047 ml | 0.237 ml | 0.474 ml |
biological activity | TNO155 is an inhibitor of protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2 /src homology region 2 domain phosphatase /PTPN11), with a corresponding IC50 value of 0.011 μM. TNO155 has potential antitumor activity. |
Target | Value |
SHP-2 (Cell-free assay) | 0.011 μM |