TRANS-ANDROSTERONE
Epiandrosterone
CAS: 481-29-8
Molecular Formula: C19H30O2
TRANS-ANDROSTERONE - Names and Identifiers
| Name | Epiandrosterone |
| Synonyms | Epiandrosterone Isoandrosterone 3-Epiandrosterone TRANS-ANDROSTERONE 3beta-Androsterone trans-Androsterone 5-Epiandrosterone-17-one 3-hydroxyandrostan-17-one 3-Hydroxyandrostan-17-one 5alpha-Androstan-3beta-ol-17-one (3beta)-3-hydroxyandrostan-17-one 3beta-Hydroxy-5alpha-androstan-17-one 5alpha-Androstan-17-one, 3beta-hydroxy- (3beta,5alpha)-3-hydroxyandrostan-17-one Androstan-17-one, 3-hydroxy-, (3beta,5alpha)- (3beta,5alpha,9beta)-3-hydroxyandrostan-17-one (3beta,5alpha,14beta)-3-hydroxyandrostan-17-one (3beta,5alpha,9beta,14beta)-3-hydroxyandrostan-17-one (3S,5S,8R,10S,13S)-3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-one |
| CAS | 481-29-8 |
| EINECS | 207-563-3 |
| InChI | InChI=1/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12-16,20H,3-11H2,1-2H3/t12-,13-,14-,15-,16+,18-,19-/m0/s1 |
| InChIKey | QGXBDMJGAMFCBF-LUJOEAJASA-N |
TRANS-ANDROSTERONE - Physico-chemical Properties
| Molecular Formula | C19H30O2 |
| Molar Mass | 290.45 |
| Density | 1.0320 (rough estimate) |
| Melting Point | 172-174°C |
| Boling Point | 372.52°C (rough estimate) |
| Specific Rotation(α) | 91 º (c=1, CH3OH) |
| Flash Point | 176.377°C |
| Water Solubility | practically insoluble |
| Vapor Presure | 0mmHg at 25°C |
| Merck | 3609 |
| BRN | 1884007 |
| pKa | 15.14±0.60(Predicted) |
| Storage Condition | Refrigerator |
| Refractive Index | 1.4709 (estimate) |
| Physical and Chemical Properties | Melting point 171-177°C specific rotation 91 ° (c = 1, CH3OH) water-soluble practically insoluble |
| Use | For steroid drugs |
| In vitro study | Epiandrosterone is a natural metabolite of Dehydroepiandrosterone(DHEA) by 5α-reductase. Epiandrosterone is formed in peripheral tissues, released into the blood circulation, and finally excreted in the urine. Epiandrosterone acts weakly as an androgen, but is widely believed to inhibit the pentose phosphate pathway (PPP) and reduce intracellular NADPH levels. Epiandrosterone reduces NO-induced pulmonary artery relaxation, although Epiandrosterone acts on isolated lungs, inhibits angiotensin II and hypoxia-induced vasoconstriction, and relaxes isolated pulmonary arteries precontracted with KCl. |
TRANS-ANDROSTERONE - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 21 |
| HS Code | 29144000 |
TRANS-ANDROSTERONE - Reference Information
| LogP | 3.751 |
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| biological activity | Epiandrosterone (3β-androsterone, EpiA) is a steroid hormone with weak androgen activity and a natural metabolite of DHEA. |
| Target | Value |
| use | for steroidal hormone drugs |
| Production method | Use 5-androstene-3 β-ol-17-one 3-acetate to catalyze hydrogenation with palladium to obtain androstene-3β-ol-17one 3-acetate, and then hydrolyze with sodium hydroxide solution to obtain the product. |
Last Update：2024-04-09 20:52:54
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Product Name: Rocuronium Bromide Impurity 22 (Epiandrosterone) Visit Supplier Webpage Request for quotationCAS: 481-29-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: Epiandrosterone Request for quotation
CAS: 481-29-8
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: 13651600618
WhatsApp: +8613651600618
CAS: 481-29-8
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: 13651600618
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