TUFTSIN
TUFTSIN TUFTSIN ACETATE SALT HYDRATE
CAS: 9063-57-4
Molecular Formula: C21H40N8O6
TUFTSIN - Names and Identifiers
TUFTSIN - Physico-chemical Properties
| Molecular Formula | C21H40N8O6 |
| Molar Mass | 500.59 |
| Density | 1.48±0.1 g/cm3(Predicted) |
| pKa | 3.60±0.21(Predicted) |
| Storage Condition | −20°C |
| In vitro study | Tuftsin is a tetrapeptide, Thr-Lys-Pro-Arg, which resides in the Fc-domain of the heavy chain of immunoglobulin G. Tuftsin possesses a broad spectrum of activities related primarily to the immune system function and exerts on phagocytic cells, notably on macrophages. Tuftsin's capacity to augment cellular activation is mediated by specific receptors that are identified, characterized, and recently isolated from rabbit peritoneal granulocytes. Tuftsin, a macrophage/microglial activator, dramatically improves the clinical course of experimental autoimmune encephalomyelitis (EAE), a well-established animal model for MS. Tuftsin administration correlates with upregulation of the immunosuppressive Helper-2 Tcell (Th2) cytokine transcription factor GATA-3. Tuftsin promotes phagocytic activity for cells of monocytic origin, such as neutrophils, macrophages and microglia, all of which are thought to express Tuftsin receptors. |
TUFTSIN - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.998 ml | 9.988 ml | 19.976 ml |
| 5 mM | 0.4 ml | 1.998 ml | 3.995 ml |
| 10 mM | 0.2 ml | 0.999 ml | 1.998 ml |
| 5 mM | 0.04 ml | 0.2 ml | 0.4 ml |
Last Update：2024-01-02 23:10:35
TUFTSIN - Reference Information
| traits | Tuftsin appearance is solid powder. |
| use | Tuftsin is an immunostimulant that induces bactericidal and tumor killing activity by promoting phagocytosis, antigen presentation and cell migration. |
| biological activity | Tuftsin is a tetrapeptide. Tuftsin are macrophage/microglia activators. |
| target | human Endogenous Metabolite |
| in vitro study | Tuftsin is a tetrapeptide, Thr-Lys-Pro-Arg, which resides in the Fc-domain of the heavy chain of immunoglobulin g. Tuftsin possesses a broad spectrum of activities related primarily to the immune system function and results on phagocytic cells, notably on macrophages. Tuftsin's capacity to augment cellular activation is mediated by specific receptors that are identified, characterized, and recently isolated from rabbit peritoneal granulocytes. Tuftsin, a macrophage/microglial activator, dramatically improves the clinical course of experimental autoimmune encephalomyelitis (EAE), a well-established animalmodel for MS. Tuftsin administration correlates with upregulation of the immunosuppressive Helper-2 Tcell (Th2) cytokine transcription factor GATA-3. Tuftsin promotes phagocytic activity for cells of monocytic origin, such as neutrophils, macrophages and microglia, all of which are thought to express Tuftsin receptors. |
Last Update：2024-04-09 21:01:54
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CAS: 9063-57-4
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Product Name: TUFTSIN TUFTSIN ACETATE SALT HYDRATE Visit Supplier Webpage Request for quotation
CAS: 9063-57-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 9063-57-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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