Molecular Formula | C24H22N4O5S
|
Molar Mass | 478.52 |
Density | 1.34±0.1 g/cm3(Predicted) |
Boling Point | 716.8±70.0 °C(Predicted) |
Solubility | DMSO : ≥ 100 mg/mL (208.98 mM) |
pKa | 3.14±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Use | Taprenepag (CP-544326) is a potent, selective prostaglandin E2 receptor agonist with EC50 of 2.8 nM. |
In vitro study | Taprenepag (CP-544326) (0.01-1000 nM) increases cAMP levels in HEK293 cells expressing human EP2 (EC 50 =2.8 nM). Taprenepag has poor corneal permeability in an ex vivo rabbit corneal model. |