Name | Thiazolidine |
Synonyms | Teneint-H Ring Parent thiazolidin THIAZOLIDINE Thiazolidine 1,3-Thiazolidine 1,3-thiazolidin-3-ium Thiazole, tetrahydro- THIAZOLIDINE TETRAHYDROTHIAZOLE |
CAS | 504-78-9 |
EINECS | 208-002-5 |
InChI | InChI=1/C3H7NS/c1-2-5-3-4-1/h4H,1-3H2/p+1 |
InChIKey | OGYGFUAIIOPWQD-UHFFFAOYSA-N |
Molecular Formula | C3H7NS |
Molar Mass | 89.16 |
Density | 1.131 g/mL at 25 °C (lit.) |
Boling Point | 72-75 °C/25 mmHg (lit.) |
Flash Point | 133°F |
Vapor Presure | 1.96mmHg at 25°C |
Appearance | Liquid |
Color | Clear colorless |
pKa | 8.84±0.20(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | n20/D 1.5508(lit.) |
MDL | MFCD00005211 |
Use | Thiazolidine was used in the synthesis of homogeneous penicillamine disulphide cross-linked polypeptides. |
Hazard Symbols | C - Corrosive |
Risk Codes | 34 - Causes burns |
Safety Description | S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
UN IDs | UN 1993 3/PG 3 |
WGK Germany | 3 |
RTECS | XJ5123700 |
HS Code | 29341000 |
Hazard Class | 3 |
Packing Group | III |
Introduction | Thiazolidine is a heterocyclic organic compound with a 5-membered saturated ring, a thioether group at position 1 and an amine group at position 3. It is a sulfur analog of oxazolidine. Thiazolidine derivatives are widely used and have broad-spectrum biological activities. For example, the drug pioglitazone contains a thiazolidine ring, which is commonly used to lower blood sugar in patients with type 2 diabetes. It can also lower blood pressure and increase high-density lipoprotein levels. |
use | thiazolidine alias tetrahydrothiazole is a transparent colorless liquid and can be used as a pharmaceutical intermediate. |