Teniposide
Teniposide
CAS: 29767-20-2
Molecular Formula: C32H32O13S
Teniposide - Names and Identifiers
| Name | Teniposide |
| Synonyms | Teniposide Teniposide(VuMon) 4'-Demethylepipodophyllotoxin thenylidene glucoside 4'-Demethylepipodophyllotoxin9-(4,6-o-2-thenylidene- 4'-demethylepipodophyllotoxin-beta-d-thenylidineglucoside 4'-demethyl-epipodophyllotoxin-beta-d-thenylidene-glucosid 4'-demethyl-epipodophyllotoxin-beta-d-thenylidene-glucoside 4'-Demethylepipodophyllotoxin-9-(4,6-O-2-thenylidene β-D-glucopyranoside) 4'-demethylepipodophyllotoxin9-(4,6-o-2-thenylidene-beta-d-glucopyranoside) 4'-demethylepipodophyllotoxin9-(4,6-o-2-thenylidene-bata-d-glucopyranoside. 4'-demethyl1-o-(4,6-o,o-(2-thenylidene)-beta-d-glucopyranosyl)epipodophyllot 4'-demethyl1-o-(4,6-o,o-(2-thenylidene)-beta-d-glucopyranosyl)epipodophylloto Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-o-2-thienylidene-.beta.-D-glucopyranoside) |
| CAS | 29767-20-2 |
| EINECS | 249-831-2 |
| InChI | InChI=1/C32H32O13S/c1-37-19-6-13(7-20(38-2)25(19)33)23-14-8-17-18(42-12-41-17)9-15(14)28(16-10-39-30(36)24(16)23)44-32-27(35)26(34)29-21(43-32)11-40-31(45-29)22-4-3-5-46-22/h3-9,16,21,23-24,26-29,31-35H,10-12H2,1-2H3/t16?,21-,23-,24+,26-,27-,28?,29?,31-,32+/m1/s1 |
Teniposide - Physico-chemical Properties
| Molecular Formula | C32H32O13S |
| Molar Mass | 656.65 |
| Density | 1.2568 (rough estimate) |
| Melting Point | 244-247°C |
| Boling Point | 650.86°C (rough estimate) |
| Specific Rotation(α) | D20 -107° (9:1 chloroform/methanol) |
| Flash Point | 476.5°C |
| Solubility | Soluble in acetone, dimethyl formamide, methanol (slightly), and DMSO (10 mg/ml). Insolub |
| Vapor Presure | 7.18E-32mmHg at 25°C |
| Appearance | powder |
| Color | white to beige |
| Maximum wavelength(λmax) | ['283nm(MeOH)(lit.)'] |
| Merck | 14,9145 |
| pKa | 10.13(at 25℃) |
| Storage Condition | -20°C |
| Stability | Hygroscopic |
| Sensitive | Sensitive to heat |
| Refractive Index | 1.5530 (estimate) |
| Use | For leukemia, Malignant lymphoma, neuroblastoma, bladder cancer and small cell lung cancer. |
Teniposide - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R45 - May cause cancer |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S53 - Avoid exposure - obtain special instructions before use. |
| UN IDs | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
| RTECS | KC0180000 |
| HS Code | 29349990 |
| Toxicity | LD50 intraperitoneal in mouse: 29570ug/kg |
Teniposide - Introduction
Teniposide is a chemotherapeutic drug, mainly used to treat acute lymphoblastic leukemia (ALL) in children.
Last Update：2022-10-16 17:24:21
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