Thiol-PEG-AA,HS-PEG-COOH - Names and Identifiers
Thiol-PEG-AA,HS-PEG-COOH - Physico-chemical Properties
Molecular Formula | C11H21NO5S
|
Molar Mass | 279.35314 |
Storage Condition | -20℃ |
Thiol-PEG-AA,HS-PEG-COOH - Reference
Reference Show more | 1. Liu, Yan, et al. "A smart switchable bioinspired copper foam responding to different pH droplets for reversible oil–water separation." Journal of Materials Chemistry A 5.6 (2017): 2603-2612. |
Thiol-PEG-AA,HS-PEG-COOH - Introduction
Thiol-PEG-AA, HS-PEG-COOH(Thiol-PEG-AA, HS-PEG-COOH) is a chemical compound with the following properties and uses:
Nature:
1. Thiol is a kind of functional group containing sulfur atom, which has high sulfur affinity.
2. PEG is the abbreviation of polyethylene glycol (polyethylene glycol), which is a water-soluble polymer compound, which can be used to improve the stability and biocompatibility of drugs and nanomaterials.
3. Polyethylene glycol carboxyl group (COOH) is the end group modification of PEG, with carboxyl functional groups, with hydrophilic.
Use:
1. Thiol-PEG-AA,HS-PEG-COOH is often used in the preparation of drugs and functional modification of nanomaterials.
2. Sulfhydryl can react with metal ions, metal surfaces, etc. to generate gold-sulfur bonds for the preparation of metal nanoparticles or the preparation of metal nanomaterials.
3. Polyethylene glycol carboxyl groups can provide hydrophilicity and biocompatibility when preparing nanocarriers or nanoparticles.
Preparation Method:
Thiol-PEG-AA, the preparation of HS-PEG-COOH can be achieved by introducing thiol and carboxyl functional groups on the PEG molecule. A specific method is to react an appropriate thiolating reagent (such as mercaptoethanol) and a carboxylating reagent (such as acid chloride) with a polyethylene glycol molecule to obtain a Thiol-PEG-AA,HS-PEG-COOH.
Safety Information:
1. Thiol-PEG-AA, the HS-PEG-COOH is usually relatively safe under normal use and operating conditions, but the correct laboratory operation safety regulations should be followed.
2. in use, attention should be paid to avoid contact with skin, eyes and oral mucosa, so as not to cause irritation.
3. should be stored in a sealed, dry, cool place, away from the fire and combustibles.
4. When handling the compound, appropriate personal protective measures should be taken, such as wearing gloves and protective glasses. In case of accidental exposure or ingestion, wash and seek medical attention.
Last Update:2024-04-09 02:00:56