Thiol-PEG-Hydroxyl

Thiol-PEG-Hydroxyl - Names and Identifiers

Name	HS-PEG-OH
Synonyms	HS-PEG-OH SH-PEG-OH Thiol-PEG-Hydroxyl

Thiol-PEG-Hydroxyl - Physico-chemical Properties

Storage Condition

-20℃

Thiol-PEG-Hydroxyl - Introduction

HS-PEG-OH(HS-PEG-OH) is a polymer compound with thiol and hydroxyl functional groups. Its properties are as follows:

1. Thiol (-SH): Thiol is an active functional group, which can react with other substances containing reactive functional groups, such as the formation of disulfide bonds or metal ions. Sulfhydryl groups can also be used as catalysts for certain chemical reactions.

2. Polyethylene glycol (PEG): Polyethylene glycol is a polymer compound with good water solubility and biocompatibility. It is commonly used in drug delivery systems, biomaterials, and bioengineering.

The purpose of the HS-PEG-OH is as follows:

1. Drug delivery system: HS-PEG-OH can be used as a carrier for drugs, covalently binding drugs to polymers through chemical reactions to enhance their stability and biodegradability.

2. biologically active modifier: HS-PEG-OH can form a modified substance with specific biological activity through the reaction of thiol groups with biological molecules, such as enzymes, antibodies, etc., for biosensors, medical diagnostics and other applications.

3. surface modifier: HS-PEG-OH modified on the surface of the material can improve its anti-pollution performance, biocompatibility and bioadhesion, and is often used in the preparation of biological materials and medical devices.

Production Method: Generally, HS-PEG-OH can be synthesized by reacting a hydroxyl-modified polyethylene glycol with a thiolating reagent (e. g., mercaptoethanol). The synthesis process requires certain reaction conditions and catalysts.

Safety information: HS-PEG-OH is generally considered to be relatively safe, but the following matters should be paid attention to during use:

1. Avoid exposing it to air to prevent the oxidation of sulfhydryl groups.
2. avoid contact with skin and eyes, if there is contact should immediately rinse with plenty of water. If discomfort occurs, seek medical help.
3. Avoid inhaling the gas of powder or solution, and maintain a well-ventilated operating environment.
4. Follow safe operating procedures during operation, and handle and store according to the recommendations provided in the relevant safety data sheet of the chemical.

Last Update：2024-04-09 18:58:34