Thiophene-2-sulfonamide
Thiophene-2-sulfonamide
CAS: 6339-87-3
Molecular Formula: C4H5NO2S2
Thiophene-2-sulfonamide - Names and Identifiers
| Name | Thiophene-2-sulfonamide |
| Synonyms | 2-Thienylsulfonamide Thiophene-2-sulfonamide Thiophene-α-sulfonamide THIOPHENE-2-SULFONAMIDE THIOPHENE-α-SULFONAMIDE Thiophene-2-sulphonamide THIOPHENE-ALPHA-SULFONAMIDE Thiophene-alpha-sulfonamide THIOPHENE-2-SULFONIC ACID AMIDE 2-Thiophenesulfonamide(6CI,7CI,8CI,9CI) |
| CAS | 6339-87-3 |
| InChI | InChI=1/C4H5NO2S2/c5-9(6,7)4-2-1-3-8-4/h1-3H,(H2,5,6,7) |
Thiophene-2-sulfonamide - Physico-chemical Properties
| Molecular Formula | C4H5NO2S2 |
| Molar Mass | 163.22 |
| Density | 1.513±0.06 g/cm3(Predicted) |
| Melting Point | 137-141 °C |
| Boling Point | 338.1±34.0 °C(Predicted) |
| Flash Point | 158.3°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 0.0001mmHg at 25°C |
| Appearance | Yellow-like solid |
| Color | White to Light yellow to Light orange |
| pKa | 9.94±0.60(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.608 |
| MDL | MFCD00185853 |
Thiophene-2-sulfonamide - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| RTECS | XN0294000 |
| HS Code | 29350090 |
Thiophene-2-sulfonamide - Introduction
Thiophene-2-sulfonamide is an organic compound with a chemical formula of C4H5NO2S and a thiophene ring and a sulfonamide group in the structure. The following is a description of some of the properties, uses, methods and safety information of the Thiophene-2-sulfonamide:
Nature:
-Appearance: The Thiophene-2-sulfonamide is white to yellowish crystalline or powdery solid.
-Solubility: Soluble in some organic solvents such as dimethyl sulfoxide and dimethylformamide, insoluble in water.
-Melting point: about 70-74 ℃.
Use:
-Chemical synthesis intermediates: Thiophene-2-sulfonamide can be used as intermediates in organic synthesis for the synthesis of other compounds.
-Drug research and development: The compound has some biological activities, so it may have application potential in drug research and development.
Preparation Method:
The preparation of Thiophene-2-sulfonamide is commonly used in two steps:
1. First, 2-thiophenecarboxaldehyde is reacted with thionamide to generate 2-thiophenecarboxaldehyde thionamide adduct.
2. Then, the adduct is heated under alkaline conditions, and a contraction reaction will occur to obtain Thiophene-2-sulfonamide.
Safety Information:
The safety of Thiophene-2-sulfonamide is better, but as an organic compound, you still need to pay attention to the following matters:
-Storage: It should be stored in a dry, dark and sealed container, away from fire and oxidizing agents.
-Use: Wear appropriate protective equipment such as glasses, gloves and lab coats when using.
-Waste disposal: Disposal shall be carried out in strict accordance with local and legal regulations.
It should be noted that the information provided above is for reference only. Please follow the specific laboratory regulations and safe operating procedures when actually operating or using.
Nature:
-Appearance: The Thiophene-2-sulfonamide is white to yellowish crystalline or powdery solid.
-Solubility: Soluble in some organic solvents such as dimethyl sulfoxide and dimethylformamide, insoluble in water.
-Melting point: about 70-74 ℃.
Use:
-Chemical synthesis intermediates: Thiophene-2-sulfonamide can be used as intermediates in organic synthesis for the synthesis of other compounds.
-Drug research and development: The compound has some biological activities, so it may have application potential in drug research and development.
Preparation Method:
The preparation of Thiophene-2-sulfonamide is commonly used in two steps:
1. First, 2-thiophenecarboxaldehyde is reacted with thionamide to generate 2-thiophenecarboxaldehyde thionamide adduct.
2. Then, the adduct is heated under alkaline conditions, and a contraction reaction will occur to obtain Thiophene-2-sulfonamide.
Safety Information:
The safety of Thiophene-2-sulfonamide is better, but as an organic compound, you still need to pay attention to the following matters:
-Storage: It should be stored in a dry, dark and sealed container, away from fire and oxidizing agents.
-Use: Wear appropriate protective equipment such as glasses, gloves and lab coats when using.
-Waste disposal: Disposal shall be carried out in strict accordance with local and legal regulations.
It should be noted that the information provided above is for reference only. Please follow the specific laboratory regulations and safe operating procedures when actually operating or using.
Last Update：2024-04-09 21:01:54
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CAS: 6339-87-3
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CAS: 6339-87-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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