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Ticargrelor

(1S,2S,3R,5S)-3-[7-[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino]-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

CAS: 274693-27-5

Molecular Formula: C23H28F2N6O4S

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Ticargrelor - Names and Identifiers

Name (1S,2S,3R,5S)-3-[7-[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino]-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
Synonyms Possia
AZD6140
Brilinta
Ticagrelo
Ticagrelor
AR-C126532
Ticargrelor
AR-C 126532XX
Ticagrelor Standards
Ticagrelor and intermediates
(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
(1S,2S,3R,5S)-3-[7-[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino]-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
1,2-Cyclopentanediol, 3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)-
CAS 274693-27-5
EINECS 619-540-9
InChI InChI=1/C23H28F2N6O4S/c1-2-7-36-23-27-21(26-15-9-12(15)11-3-4-13(24)14(25)8-11)18-22(28-23)31(30-29-18)16-10-17(35-6-5-32)20(34)19(16)33/h3-4,8,12,15-17,19-20,32-34H,2,5-7,9-10H2,1H3,(H,26,27,28)/t12-,15?,16?,17-,19-,20+/m0/s1

Ticargrelor - Physico-chemical Properties

Molecular FormulaC23H28F2N6O4S
Molar Mass522.57
Density1.67
Melting Point138-140°C
Boling Point777.6±70.0 °C(Predicted)
Solubility DMSO 105 mg/mL Water <1 mg/mL Ethanol 53 mg/mL
AppearanceSolid
ColorWhite to Off-White
pKa13.26±0.70(Predicted)
Storage ConditionKeep in dark place,Inert atmosphere,Store in freezer, under -20°C
StabilityHygroscopic
Refractive Index1.744
UseA reversible antagonist of the platelet purinergic P2Y12 receptor

Ticargrelor - Risk and Safety

Safety Description24/25 - Avoid contact with skin and eyes.
HS Code29335990

Ticargrelor - Reference

Reference
Show more
1. Yin, Qiyang, et al. "JLX001 improves myocardial Ischemia-reperfusion injury by activating Jak2-Stat3 pathway." Life Sciences 257 (2020): 118083.https://doi.org/10.1016/j.lfs.2020.118083
2. [IF=3.647] Qiyang Yin et al."JLX001 improves myocardial ischemia-reperfusion injury by activating Jak2-Stat3 pathway."Life Sci. 2020 Sep;257:118083
3. [IF=7.328] Xiao Fu et al."Construction of novel antiplatelet modified polyethersulfone membrane and study into its blood compatibility."Mat Sci Eng C-Mater. 2022 Jan;:112659
Ticargrelor
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Email: yeqim@boyechemicals.com
Mobile: 86-15387090420
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Email: 2853786052@qq.com
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Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: (1S,2S,3R,5S)-3-[7-[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino]-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol Request for quotation
CAS: 274693-27-5
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Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
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Shanghai Yuanye Bio-Technology Co., Ltd.
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Product Name: Ticagrelor Visit Supplier Webpage Request for quotation
CAS: 274693-27-5
Tel: 18301782025
Email: 3008007409@qq.com
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