Tonephin
Vasotocin
CAS: 9034-50-8;11000-17-2
Molecular Formula: C43H67N15O12S2
Tonephin - Names and Identifiers
Tonephin - Physico-chemical Properties
| Molecular Formula | C43H67N15O12S2 |
| Molar Mass | 1050.22 |
| Storage Condition | -20℃ |
Tonephin - Introduction
Sequence: Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 Disulfide bridge
Last Update：2022-10-16 17:30:00
Tonephin - Reference Information
| Overview | vasopressin (antidiuretic, ADH), also known as antidiuretic hormone, halpantam cardiac, vascular Nervousness peptide, vasopressin, bipressin.. A 9-peptide hormone synthesized primarily by the supraoptic nucleus of the hypothalamus and then sent to the pituitary for storage. It is released into the blood when needed by the body. With antidiuretic, contraction of small arteries and capillaries to increase blood pressure, hemostasis and excitement of colon and bladder smooth muscle and other effects. It is used for diabetes insipidus, hemostasis in acute bleeding of esophageal varices, surgery Shock, enteroparalysis, bladder paralysis and diagnosis of central diabetes insipidus. |
| pharmacological effects | This product has a direct antidiuretic effect on the kidney, but also can shrink the surrounding blood vessels, and cause intestinal, contractions of the gallbladder and bladder. This product has almost no oxytocin effect. |
| Application | 1. For the treatment of central diabetes insipidus. 2. For the initial treatment of polyuria after brain surgery or head trauma. 3. For other drugs with poor efficacy of abdominal muscle relaxation. |
| usage and dosage | Posterior pituitary injection (aqueous solution): 3~6 U, dissolved in 20 ml saline or glucose injection, slow injection in more than 10 minutes. For respiratory tract or gastrointestinal bleeding: intravenous infusion of 6~12 U dissolved in 5% glucose injection 500 slowly drip. Tannic acid vasopressin (diabetes insipidus) (oil): 4~20 U/time, intramuscular injection, can maintain 48~96 hours. Posterior pituitary powder: for nasal inhalation, 15~30 mg each time, 2~4 times a day. |
| adverse reactions | high dose can cause Nausea, hypertension, water and sodium retention, chest pain, myocardial ischemia or infarction, occasional allergic reactions, such as rash, Fever, bronchospasm and Shock. |
| contraindication | 1. Hypertension. 2. Coronary artery disease. 3. Arteriosclerosis. 4. Patients with heart failure and pregnant women. 5. Allergic to this product. |
| note | 1. Before injection, shake for more than 5 minutes to make the bottom edge of the bottle free of brown-red pellet. 2. Must be injected in the muscle. 3. Effect of Last injection before the next dose. 4. Avoid excessive drinking during medication. |
| Main reference material | /productchemicalplasticesb12131279.htm [1] Chen Jisheng, editor-in-chief. New clinical pharmacology. Beijing: Chinese Medicine Press. 2013. [2] Lu Fengxiang, Edited by Yang Yu. Handbook of clinical practical medicine. Nanjing: Jiangsu Science and Technology Publishing House. 2008. Page 612. |
Last Update：2024-04-09 20:52:54
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Product Name: Vasopressin Visit Supplier Webpage Request for quotationCAS: 11000-17-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: Vasotocin Request for quotation
CAS: 11000-17-2
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: 13651600618
WhatsApp: +8613651600618
CAS: 11000-17-2
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: 13651600618
WhatsApp: +8613651600618
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