Tosylurethane

Name	Tosylurethane
Synonyms	Tosylurethane ethyl tosylcarbaMate Gliclazide IMpurity C Tosylcarbamic acid ethyl ester ethyl n-(4-methylphenyl)sulfonylcarbamate Ethyl [(4-methylphenyl)sulphonyl]carbamate N-(p-Tolylsulfonyl)carbamic acid ethyl ester N-(4-methylphenyl)sulfonylcarbamic acid ethyl ester 3-ethyl-4-methylbenzenesulfonic acid carbamoyl ester
CAS	5577-13-9
EINECS	2269529

Molecular Formula	C10H13NO4S
Molar Mass	243.28
Density	1.38 at 20℃
Melting Point	82-84oC
Boling Point	272℃ at 100.8-101kPa
Solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
Vapor Presure	1.8-7.9Pa at 20-25℃
Appearance	Solid
Color	White
Storage Condition	Sealed in dry,Room Temperature

LogP	0.73-1.7 at 23℃ and pH2-7
surface tension	63.8mN/m at 1g/L and 20 ℃
biological activity	Ethyl tosylcarbamate is an intermediate in the synthesis of Gliclazide (G409877). Gliclazide is a whole-cell β-cell ATP-sensitive potassium flow (potassium currents) blocker with an IC50 of 184 nM.

Last Update：2024-04-09 20:52:54

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CAS: 5577-13-9
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QQ: 3008007409

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Tosylurethane

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