Tri(o-anisyl)phosphine

Tri(o-anisyl)phosphine - Names and Identifiers

Name	Tris-(2-methoxyphenyl)-phosphine
Synonyms	Tri(o-anisyl)phosphine TRIS(O-ANISYL)PHOSPHINE TRIS-(2-ANISYL)PHOSPHINE TRI(2-METHOXYPHENYL)PHOSPHINE Tris(o-methoxyphenyl)phosphine tris(2-methoxyphenyl)phosphane TRIS(O-METHOXYPHENYL)PHOSPHINE Tris(2-methoxyphenyl)phosphine TRIS(2-METHOXYPHENYL)PHOSPHINE Tris-(2-methoxyphenyl)-phosphine Phosphine, tris(2-methoxyphenyl)-
CAS	4731-65-1
EINECS	225-235-8
InChI	InChI=1/C21H21O3P/c1-22-16-10-4-7-13-19(16)25(20-14-8-5-11-17(20)23-2)21-15-9-6-12-18(21)24-3/h4-15H,1-3H3
InChIKey	IIOSDXGZLBPOHD-UHFFFAOYSA-N

Tri(o-anisyl)phosphine - Physico-chemical Properties

Molecular Formula	C21H21O3P
Molar Mass	352.36
Melting Point	204-208 °C
Boling Point	477.3±40.0 °C(Predicted)
Flash Point	302.5°C
Water Solubility	Slightly soluble in water.
Vapor Presure	8.19E-09mmHg at 25°C
Appearance	White powder or crystal
Color	Colorless to yellow or pale orange
BRN	2776186
Storage Condition	Inert atmosphere,Room Temperature
Sensitive	Air Sensitive
MDL	MFCD00014892

Tri(o-anisyl)phosphine - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3
TSCA	No
HS Code	29319090

Tri(o-anisyl)phosphine - Reference Information

Introduction

Tris (2-methoxyphenyl) phosphine is abbreviated as TOMPP, O-Anisyl3P, which can be prepared by the reaction of anisole and phosphorus trichloride. It has been reported that it can be used to prepare a new luminescent material of cuprous complex.

Preparation

Connect a 2-liter reaction vessel equipped with a thermometer, a mechanical stirrer, a drip funnel and a reflux condenser to an inert gas source, and fill 113g(1.04mol) of anisole and 250
ml of MTBE. After degassing, 440ml(0.70mol) of n-butyl lithium (1.6M in hexane) was added within 1 hour, during which the temperature gradually increased to reflux temperature (about 60°C). After holding at this temperature for 16 hours, the reactor contents were cooled to ambient temperature (at this time, GC analysis showed that the conversion rate of n-butyl lithium was>

99%, and the corresponding amount of 2-thioanisole was formed). Next, a mixture of 100ml of MTBE and 19.3ml(31.0g,0.225mol) of phosphorus trichloride is added at a rate that the temperature of the reaction mixture does not exceed 30°C. After the addition is complete, the white/yellow suspension is stirred for a further 4 hours. Subsequently, 30ml of water was added and the white precipitate was filtered out. Next, the white solid was washed with methanol (2 × 200ml), filtered, and dried under vacuum (1mbar,60°C). Yield: 63.4g(80%) fine white powder, according to 1H
NMR and 31P NMR, it is> 99% pure TOMPP.

Last Update：2024-04-10 22:29:15