TriMethylsilyl-4-prnty
5-TRIMETHYLSILYL-4-PENTYN-1-OL
CAS: 13224-84-5
Molecular Formula: C8H16OSi
TriMethylsilyl-4-prnty - Names and Identifiers
| Name | 5-TRIMETHYLSILYL-4-PENTYN-1-OL |
| Synonyms | TIMTEC-BB SBB009060 TriMethylsilyl-4-prnty 5-TRIMETHYLSILYL-4-PENTYN-1-OL 5-Trimethylsilyl-4-prntyn-1-ol 5-(Trimethylsilyl)pent-4-yn-1-ol 5-(TRIMETHYLSILYL)-4-PENTYN-1-OL 5-(triMethylsilyl)pent-4-yn-1-ol 4-Pentyn-1-ol, 5-(trimethylsilyl)- |
| CAS | 13224-84-5 |
| InChI | InChI=1/C8H16OSi/c1-10(2,3)8-6-4-5-7-9/h9H,4-5,7H2,1-3H3 |
TriMethylsilyl-4-prnty - Physico-chemical Properties
| Molecular Formula | C8H16OSi |
| Molar Mass | 156.3 |
| Density | 0.861 g/mL at 25 °C |
| Boling Point | 76 °C/15 mmHg (lit.) |
| Flash Point | 184°F |
| Vapor Presure | 0.154mmHg at 25°C |
| Specific Gravity | 0.852 |
| pKa | 14.97±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | n 20/D 1.457 |
TriMethylsilyl-4-prnty - Risk and Safety
| Risk Codes | 10 - Flammable |
| Safety Description | 16 - Keep away from sources of ignition. |
| UN IDs | 1987 |
| WGK Germany | 3 |
| HS Code | 29310099 |
TriMethylsilyl-4-prnty - Introduction
5-(Trimethylsilyl)-4-pentyn-1-ol, also known as TMSC ⋅ C≡ C⋅ CH2 ⋅ OH, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
1. appearance: colorless liquid.
2. molecular formula: C9H18OSi.
3. Molecular weight: 174.32g/mol.
4. Melting point:-70°C.
5. Boiling point: 64-65°C.
6. density: 0.801g/cm³.
7. Solubility: Soluble in organic solvents, such as ether, tetrahydrofuran and dimethylformamide.
Use:
1. TMSC • C ≡ C • CH2 • OH can be used as an important reagent in organic synthesis, can participate in the synthesis of sawcarbazole, and has potential medical and biological applications.
2. It can be used as a reagent in cross-coupling reactions to construct carbon-carbon bonds.
3. Due to its very active nucleophilic-acceptor properties, TMSC ⋅ C≡ C≡CH2-OH can also be used to synthesize various organic compounds.
Preparation Method:
The preparation of TMSC ⋅ C≡ C⋅ CH2 ⋅ OH can be achieved by a variety of methods. A common preparation method is the reaction of trimethyl (pentynyl) silane and methanol in the presence of cerium (IV) chloroformate.
Safety Information:
1. TMSC • C≡ C • CH2 • OH should be careful to prevent contact with oxygen during storage or use, because it may burn in the air.
2. Avoid prolonged exposure to high temperatures and fire sources to prevent explosions.
3. Use should wear appropriate protective gloves and goggles, and operate in a well-ventilated environment.
4. When using and handling, care should be taken to avoid skin and eye contact to avoid irritation and damage.
5. Keep away from flammable and explosive substances during storage and handling.
Please note that TMSC ⋅ C≡ C⋅ CH2 ⋅ OH is a chemical reagent and must be operated under suitable laboratory conditions by professionals with laboratory safety knowledge and experience.
Nature:
1. appearance: colorless liquid.
2. molecular formula: C9H18OSi.
3. Molecular weight: 174.32g/mol.
4. Melting point:-70°C.
5. Boiling point: 64-65°C.
6. density: 0.801g/cm³.
7. Solubility: Soluble in organic solvents, such as ether, tetrahydrofuran and dimethylformamide.
Use:
1. TMSC • C ≡ C • CH2 • OH can be used as an important reagent in organic synthesis, can participate in the synthesis of sawcarbazole, and has potential medical and biological applications.
2. It can be used as a reagent in cross-coupling reactions to construct carbon-carbon bonds.
3. Due to its very active nucleophilic-acceptor properties, TMSC ⋅ C≡ C≡CH2-OH can also be used to synthesize various organic compounds.
Preparation Method:
The preparation of TMSC ⋅ C≡ C⋅ CH2 ⋅ OH can be achieved by a variety of methods. A common preparation method is the reaction of trimethyl (pentynyl) silane and methanol in the presence of cerium (IV) chloroformate.
Safety Information:
1. TMSC • C≡ C • CH2 • OH should be careful to prevent contact with oxygen during storage or use, because it may burn in the air.
2. Avoid prolonged exposure to high temperatures and fire sources to prevent explosions.
3. Use should wear appropriate protective gloves and goggles, and operate in a well-ventilated environment.
4. When using and handling, care should be taken to avoid skin and eye contact to avoid irritation and damage.
5. Keep away from flammable and explosive substances during storage and handling.
Please note that TMSC ⋅ C≡ C⋅ CH2 ⋅ OH is a chemical reagent and must be operated under suitable laboratory conditions by professionals with laboratory safety knowledge and experience.
Last Update：2024-04-09 21:04:16
