Tributyrin
Tributyrin
CAS: 60-01-5
Molecular Formula: C15H26O6
Tributyrin - Names and Identifiers
| Name | Tributyrin |
| Synonyms | BUTYRIN FEMA 2223 Tributyrin Glycery tributyrate GLYCERYL TRIBUTYRATE Glycerol tributyrate GLYCEROL TRIBUTYRATE Glyceryl tributyrate GLYCEROL TRI-N-BUTYRATE 1,2,3-TRIBUTYRYLGLYCEROL propane-1,2,3-triyl tributanoate |
| CAS | 60-01-5 |
| EINECS | 200-451-5 |
| InChIKey | UYXTWWCETRIEDR-UHFFFAOYSA-N |
Tributyrin - Physico-chemical Properties
| Molecular Formula | C15H26O6 |
| Molar Mass | 302.36 |
| Density | 1.0335 |
| Melting Point | -75 °C |
| Boling Point | 305 °C |
| Flash Point | 345°F |
| JECFA Number | 922 |
| Water Solubility | Not miscible in water. |
| Solubility | Soluble in ethanol, ether, acetone and other organic solvents, insoluble in water. |
| Vapor Presure | 0.000722mmHg at 25°C |
| Appearance | Colorless liquid |
| Color | Clear colorless to yellow |
| Merck | 14,9620 |
| BRN | 1714746 |
| Storage Condition | Store at RT. |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Refractive Index | n20/D 1.435(lit.) |
| MDL | MFCD00009392 |
| Physical and Chemical Properties | White nearly oily liquid. Almost no smell, slightly fat aroma. Boiling point 308 °c, melting point -75 °c. Soluble in ethanol, chloroform and ether, very difficult to dissolve in water (0.010%). Natural products are found in tallow. |
Tributyrin - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 1 |
| RTECS | ET7350000 |
| TSCA | Yes |
| HS Code | 29171900 |
Tributyrin - Reference
| Reference Show more | 1. Zhao Yan, Xiao Zhigang, Ren Haibin, etc. Lipase-catalyzed transesterification of rice oil to prepare low-calorie structural lipids and its kinetics [J]. Chinese Journal of cereal and oil, 2017, 032(003):42-47. 2. Jiya-Mei, Wang Li-mei, Qi Bin. Breeding of Yersinia yeast with high lipase production by atmospheric pressure and room temperature plasma mutation [J]. Food and machinery, 2020,36(11):10-15. 3. [IF = 5.64] Li Jie et al."Investigation of the mineral Acid Bacteria in Kazak Cheese and Their Contributions to Cheese Fermentation." Front Microbiol. 2020 Mar;0:228 4. [IF = 5.64] Jing Xiao et al."Evaluation of the Effect of Auxiliary Starter Yeasts With Enzyme Activities on Kazak Cheese Quality and Flavor."Front Microbiol. 2020; 11: 614208 5. [IF=3.757] Xiaochun Zheng et al.Diversity and potential function of bacterial communities during milk fermentation of Kazak artisanal cheese.Process Biochem. 2021 Dec;111:191 |
Tributyrin - Introduction
There is a bitter taste.
Last Update：2022-10-16 17:26:54
Tributyrin - Reference Information
| FEMA | 2223 | (TRI-)BUTYRIN |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| physical and chemical properties | a short-chain fatty acid ester consisting of three molecules of butyric acid and one molecule of glycerol, because of its insoluble in water, soluble in ethyl ether and ethanol and other organic solvents, and low melting point and high boiling point of physical properties (melting point:-75 ℃, Boiling Point: 305~310 ℃), therefore, under the conditions of high temperature, light and granulation, its physical and chemical properties are basically unchanged, which is suitable for the production process of various types of feed processing. |
| Use | glycerol tributyl Ester is lipidated from one molecule of glycerol and three-molecule butyric acid through a three-step chemical reaction procedure. Glycerol tributyl esters are naturally found in animal fats, vegetable oils, dairy products, etc., and are mainly used in the processing of margarines and as feed additives. In the biological science and technology as screening, characterization of esterase substrate. spices. Mainly used in the preparation of cream, margarine and other spices, also used as solvent spices. artificial food flavor. used as substrate for determination of esterase and lipase. |
| feed additive | glycerol tributyl Ester is a short-chain fatty acid ester consisting of 4 carbon atoms, which is a colorless and nearly oily liquid, slightly fat flavor, can smoothly through the gastrointestinal tract, and is slowly decomposed into butyric acid, and then reach the back end of the intestinal tract, play the corresponding physiological effects. Studies have reported that glycerol tributyl ester can promote the growth of intestinal villi, enhance the digestion of nutrients, maintain the balance of intestinal flora, enhance tight junction, promote mucin secretion and improve immunity, in order to improve the production performance of animals. Therefore, the addition of glycerol tributyl Ester in feed has become a nutritional strategy to improve the intestinal barrier function of animals and promote the growth of animals, and has been widely used in the process of animal husbandry. |
| assay | was determined by method one in the ester assay (OT-18). The amount of the sample was 1.5g. The equivalence factor (e) in the calculation is taken as 50.40. Or according to Gas chromatography (GT-10-4) using non-polar column method. |
| toxicity | GRAS(FEMA). Ld503200 mg/kg (rat, oral). |
| usage limit | FEMA(mg/kg): Soft drink 0.10; Cold drink 0.04; Candy 0.33~1000; baked goods 290; Pudding 0.36; Margarine 2.0~5.0. |
| production method | is obtained by heating esterification of glycerol and excess butyric acid. |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 15:16:51
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View History
Tributyrin
527-09-3
ethyl 5-fluoroindole-2-carboxylate
2-Methylthiophene
71271-24-4
Beta-Ala-Pro-Dab-NHBzl
4-Bromophenyl phenyl ketone
53494-70-5
1-(4-chlorophenyl)-2-(2-imino-3-propyl-2,3-dihydro-1H-benzimidazol-1-yl)ethanol
1266975-27-2
527-09-3
ethyl 5-fluoroindole-2-carboxylate
2-Methylthiophene
71271-24-4
Beta-Ala-Pro-Dab-NHBzl
4-Bromophenyl phenyl ketone
53494-70-5
1-(4-chlorophenyl)-2-(2-imino-3-propyl-2,3-dihydro-1H-benzimidazol-1-yl)ethanol
1266975-27-2