Name | Triptophenolide |
Synonyms | HYPOLIDE Triptophenolide TRIPTOPHENOLIDE Tryptophenolide Triptophenolide, BR Triptophenolide (Hypolide Hypolide (Triptophenolide) 6-hydroxy-9b-methyl-7-propan-2-yl-3,3b,4,5,10,11-hexahydronaphtho[2,1-e]isobenzofuran-1-one 6-hydroxy-9b-methyl-7-propan-2-yl-3,3b,4,5,10,11-hexahydronaphtho[2,1-e][2]benzofuran-1-one (3bR,9bS)-6-hydroxy-9b-methyl-7-(propan-2-yl)-3b,4,5,9b,10,11-hexahydrophenanthro[1,2-c]furan-1(3H)-one Phenanthro(1,2-c)furan-1(3H)-one, 3b,4,5,9b,10,11-hexahydro-6-hydroxy-9b-methyl-7-(1-methylethyl)-, (3bR-trans)- |
CAS | 74285-86-2 |
InChI | InChI=1/C20H24O3/c1-11(2)12-4-6-16-14(18(12)21)5-7-17-15-10-23-19(22)13(15)8-9-20(16,17)3/h4,6,11,17,21H,5,7-10H2,1-3H3/t17-,20+/m0/s1 |
Molecular Formula | C20H24O3 |
Molar Mass | 312.4 |
Density | 1.21 |
Melting Point | 232-233℃ |
Boling Point | 490.0±45.0 °C(Predicted) |
Specific Rotation(α) | (c, 0.25 in MeOH)+37.6 |
Flash Point | 202.4°C |
Solubility | Soluble in chloroform, ethyl acetate, acetone and other organic solvents, hardly soluble in water. |
Vapor Presure | 3.16E-10mmHg at 25°C |
Appearance | Colorless needle crystal |
pKa | 10.63±0.40(Predicted) |
Storage Condition | 2-8℃ |
Refractive Index | 1.603 |
MDL | MFCD00210567 |
Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from the mountain begonia, Tripterygium wilfordii root bark. |
Reference Show more | 1. Wu Xiaoyi, Zhang Keyi, Zhang Rui, etc. Optimization of extraction process of total terpenoids from suspension cells of Tripterygium wilfordii based on multi-index comprehensive score and orthogonal design [J]. China Medical leads, 2018, 015(031):25-29. 2. Guo Siyuan, Ma Baowei, Wu Xiaoyi, etc. Differences of terpenoids in leaves of Tripterygium plants [J]. World Traditional Chinese Medicine, 2018. 3. Wu Xiaoyi, Zhang Rui, Ma Yun, Meng Lingjia, Tu Li Min, Hu Tianyuan, Gao Wei. Effects of glucosinolide analog GR24 on accumulation of diterpenoid secondary metabolites in suspension cells of Tripterygium wilfordii [J]. Chinese Journal of Traditional Chinese Medicine, 2019,44(16):3582-3587. 4. [IF = 6.417] Ping Su et al."Identification and functional characterization of diterpen synthases for triptolide biosynthesis from triptyum wilfordii. Plant J. 2018 Jan;93(1):50-65 |