Name | tris(2,4-ditert-butylphenyl) phosphate |
Synonyms | AAN06119 AI3-28586 Irgafos 168 Phosphate Tris(2,4-di-tert-butylphenyl)phosphate Tri(2,4-di-tert-butylphenyl) phosphate tris(2,4-ditert-butylphenyl) phosphate Phenol, 2,4-bis(1,1-dimethylethyl)-, 1,1',1''-phosphate |
CAS | 95906-11-9 |
Molecular Formula | C42H63O4P |
Molar Mass | 662.92 |
Density | 1.007±0.06 g/cm3(Predicted) |
Boling Point | 609.8±55.0 °C(Predicted) |
Storage Condition | 2-8℃ |
Physical and Chemical Properties | Bioactive Tris(2,4-di-tert-butylphenyl)phosphate is an active compound isolated from Vitex negundo L., which has anti-inflammatory activity and inhibits secretory phospholipase A2 (sPLA2) through molecular docking. |
Use | AAN06119 is a chemical reagent. This product has not formal name. For the convenience of scientific communication, we named it by combining its Inchi key (3 letters from the first letter of each section) with the last 5 digit of its CAS#) according to MedKoo Chemical Nomenclature (https://www.medkoo.com/page/naming). |
Reference Show more | [1]. Vinuchakkaravarthy T, et al. Active compound from the leaves of Vitex negundo L. shows anti-inflammatory activity with evidence of inhibition for secretory Phospholipase A(2) through molecular docking. Bioinformation. 2011;7(4):199-206. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 1.508 ml | 7.542 ml | 15.085 ml |
5 mM | 0.302 ml | 1.508 ml | 3.017 ml |
10 mM | 0.151 ml | 0.754 ml | 1.508 ml |
5 mM | 0.03 ml | 0.151 ml | 0.302 ml |
EPA chemical information | Phenol, 2,4-bis(1,1-dimethylethyl)-, 1,1',1''-phosphate (95906-11-9) |
Target
sPLA 2
In vivo studies
Tris(2,4-di-tert-butylphenyl)phosphate (TDTBPP; 50 mg/kg and 70 mg/kg) exhibits significant anti-inflammatory activity in carrageenan induced paw odema model.
Tris(2,4-di-tert-butylphenyl)phosphate (50 mg/kg and 70 mg/kg) reduces the raw paw odema volume significantly.