Tris(benzyloxycarbonyl)arginine - Names and Identifiers
Name | N5-[imino[[(phenylmethoxy)carbonyl]amino]methyl]-N2,N5-bis[(phenylmethoxy)carbonyl]-L-ornithine
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Synonyms | NSC 120011 Z-Arg(Z)2-OH Z-Arg(Z)2-Oh Z-L-ARG(Z2)-OH Z-ARG(DI-Z)-OH Tris(benzyloxycarbonyl)arginine N-ALPHA,NG,NG-TRI-CBZ-L-ARGININE N-ALPHA,N-DELTA,N-OMEGA-TRI-Z-L-ARGININE N-ALPHA,N-OMEGA,N-OMEGA'-TRIS-Z-L-ARGININE Arginine, tricarboxy-, N2,N5,N5-tribenzyl ester, L- N-ALPHA,N-OMEGA1,N-OMEGA2-TRI CARBOBENZOXY-L-ARGININE N-ALPHA,N-DELTA,N-OMEGA-TRIBENZYLOXYCARBONYL-L-ARGININE N-ALPHA ,N-OMEGA1,N-OMEGA2-TRI CARBOBENZOXY-L-ARGININE SODIUM SALT Ornithine, N2,N5-dicarboxy-N5-(carboxyamidino)-, N2,N5,N5-tribenzyl ester, L- N~2~,N~5~-bis[(benzyloxy)carbonyl]-N~5~-{N'-[(benzyloxy)carbonyl]carbamimidoyl}ornithine N~2~,N~5~-bis[(benzyloxy)carbonyl]-N~5~-{N'-[(benzyloxy)carbonyl]carbamimidoyl}-L-ornithine N5-(Imino(((phenylmethoxy)carbonyl)amino)methyl)-N2,N5-bis((phenylmethoxy)carbonyl)-L-ornithine N5-[imino[[(phenylmethoxy)carbonyl]amino]methyl]-N2,N5-bis[(phenylmethoxy)carbonyl]-L-ornithine L-Ornithine, N5-(imino(((phenylmethoxy)carbonyl)amino)methyl)-N2,N5-bis((phenylmethoxy)carbonyl)- 2-Oxa-4,6,11-triazadodecan-12-oic acid, 10-carboxy-5-imino-3-oxo-1-phenyl-6-((phenylmethoxy)carbonyl)-, 12-(phenylmethyl) ester, (S)- 2-Oxa-4,6,11-triazadodecan-12-oic acid, 10-carboxy-5-imino-3-oxo-1-phenyl-6-((phenylmethoxy)carbonyl)-, 12-(phenylmethyl) ester, (10S)-
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CAS | 14611-34-8
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EINECS | 238-647-8 |
InChI | InChI=1/C30H32N4O8/c31-27(33-29(38)41-20-23-13-6-2-7-14-23)34(30(39)42-21-24-15-8-3-9-16-24)18-10-17-25(26(35)36)32-28(37)40-19-22-11-4-1-5-12-22/h1-9,11-16,25H,10,17-21H2,(H,32,37)(H,35,36)(H2,31,33,38)/t25-/m0/s1 |
Tris(benzyloxycarbonyl)arginine - Physico-chemical Properties
Molecular Formula | C30H32N4O8
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Molar Mass | 576.6 |
Density | 1.27±0.1 g/cm3(Predicted) |
Melting Point | 137-140°C |
Solubility | almost transparency in hot Methanol |
Appearance | Solid |
Color | White to Almost white |
pKa | 3.94±0.21(Predicted) |
Storage Condition | -15°C |
Refractive Index | 1.595 |
MDL | MFCD00038693 |
Tris(benzyloxycarbonyl)arginine - Introduction
N5-[imino[[(phenylmethoxy)carbonyl]amino]methyl]-N2,N5-bis[(phenylmethoxy)carbonyl]-L-ornithine, also known as Boc-L-arginine benzyl ester, it is an organic compound. The following is a description of its nature, use, preparation and safety information:
Property: N5-[imino[[(phenylmethoxy)carbonyl]amino]methyl]-N2,N5-bis[(phenylmethoxy)carbonyl]-L-ornithine is a white crystalline solid, it is soluble in organic solvents such as methanol and ethanol, and has lower solubility in water. It is stable at normal temperature, but may decompose under high temperature and strong acid or alkali conditions.
Use: N5-[imino[[(phenylmethoxy)carbonyl]amino]methyl]-N2,N5-bis[(phenylmethoxy)carbonyl]-L-ornithine is usually used as a protecting group in chemical synthesis. It can effectively protect the amino group of arginine to prevent its participation in the reaction. This makes it very useful in the synthesis of polypeptides and proteins, where the positional selectivity of specific reactions can be controlled.
formulation: N5-[imino[[(phenylmethoxy)carbonyl]amino]methyl]-N2,N5-bis[(phenylmethoxy)carbonyl]-L-ornithine can be prepared by reacting the Boc Group with L-arginine. This is usually obtained by reaction of benzyloxycarbonyl chloride or tert-butylcarbonyl chloride (Boc-Cl) with L-arginine under basic conditions.
Security information: N5-[imino[[(phenylmethoxy)carbonyl]amino]methyl]-N2,N5-bis[(phenylmethoxy)carbonyl]-L-ornithine can be considered relatively safe under general operating conditions. However, it is an organic compound, so care should be taken to avoid direct contact with the skin, eyes or respiratory tract. In addition, it should be used in well-ventilated laboratory conditions and stored properly to prevent the risk of fire and explosion. Detailed safety operation should be evaluated according to specific experimental conditions and material safety data sheets.
Last Update:2024-04-09 20:52:54