Molecular Formula | C15H8N2O2 |
Molar Mass | 248.24 |
Density | 1.45±0.1 g/cm3(Predicted) |
Melting Point | 258 °C(Solv: ethanol (64-17-5)) |
Boling Point | 469.3±28.0 °C(Predicted) |
Solubility | DMSO: soluble2mg/mL (warmed) |
Appearance | Solid |
Color | faint yellow to dark yellow |
pKa | -3.06±0.20(Predicted) |
Storage Condition | 2-8°C |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
MDL | MFCD00012073 |
WGK Germany | 3 |
HS Code | 29339900 |
Reference Show more | 1. Liwei He, Fangtian Fan, Xianbang Hou, Hongyan Wu, Juan Wang, Huiqin Xu, Yun Sun, 4(3H)-Quinazolone regulates innate immune signaling upon respiratory syncytial virus infection by moderately inhibiting the RIG-1 pathway in RAW264.7 cell, International Immun 2. [IF=4.411] Zhiqin Xu et al."Optimization of Extraction of Bioactive Compounds from Baphicacanthus cusia Leaves by Hydrophobic Deep Eutectic Solvents."Molecules. 2021 Jan;26(6):1729 |
biological activity | Tryptanthrin is an effective oral active intracellular Leukotriene (LT) biosynthesis inhibitor. Tryptanthrin inhibited the formation of Leukotriene in human whole blood (IC50=10 µM) and decreased LTB4 levels in a rat pleurisy model. |
target | IC50: 10 µM (LT formation in human whole blood) |