Vercyte
Pipobroman
CAS: 54-91-1
Molecular Formula: C10H16Br2N2O2
Vercyte - Names and Identifiers
| Name | Pipobroman |
| Synonyms | A-8103 Amedel Vercyte NSC-25154 Pipobroman 1,4-Bis(3-bromo-1-oxopropyl)piperadine 1,1'-(Piperazine-1,4-diyl)bis(3-bromopropan-1-one) 3-bromo-1-[4-(3-bromopropanoyl)piperazin-1-yl]propan-1-one |
| CAS | 54-91-1 |
Vercyte - Physico-chemical Properties
| Molecular Formula | C10H16Br2N2O2 |
| Molar Mass | 356.05 |
| Density | 1.691 |
| Melting Point | 106-107℃ |
| Boling Point | 487℃ |
| Flash Point | 248℃ |
| Color | Crystals from H2O |
| pKa | -0.56±0.70(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.6220 (estimate) |
Vercyte - Risk and Safety
| Toxicity | LD50 orl-rat: 220 mg/kg IYKEDH 4,467,73 |
Vercyte - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.809 ml | 14.043 ml | 28.085 ml |
| 5 mM | 0.562 ml | 2.809 ml | 5.617 ml |
| 10 mM | 0.281 ml | 1.404 ml | 2.809 ml |
| 5 mM | 0.056 ml | 0.281 ml | 0.562 ml |
Last Update：2024-01-02 23:10:35
Vercyte - Reference Information
| Biological activity | Pipobroman is a brominated derivative of piperazine and an effective alkylating agent. Pipobroman play its role by inhibiting DNA and RNA polymerase or reducing pyrimidine nucleotide incorporation into DNA. Pipobroman can be used for cancer research, including polycythemia vera, myeloproliferative tumors, AML, etc. |
| category | toxic substances |
| toxicity classification | highly toxic |
| acute toxicity | oral-rat LD50; 220 mg/kg; Oral-mouse LD50: 382 mg/kg |
| flammability hazard characteristics | combustible; combustion produces toxic nitrogen oxides and bromide smoke |
| storage and transportation characteristics | warehouse ventilation and low temperature drying; separate from food raw materials |
| fire extinguishing agent | dry powder, foam, sand, carbon dioxide, mist water |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 20:49:11
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CAS: 54-91-1
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CAS: 54-91-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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