Molecular Formula | C14H23N3OS |
Molar Mass | 281.42 |
Density | 1.101±0.06 g/cm3(Predicted) |
Boling Point | 397.0±42.0 °C(Predicted) |
Solubility | H2O: soluble10mg/mL, clear (warmed) |
Appearance | powder |
Color | off-white |
pKa | 7.34±0.40(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Physical and Chemical Properties | Guromelin oxalate (Xanomeline Oxalate):C14H23N3OS?C2H2O4. [141064-23-5]. Crystallized from acetone, melting point 148 ℃. ()-L-Gnuomelin Tartrate (Xanomeline Tartrate):C14H23N3OS?C4H6O6. [152854-19-8]. Crystallized from 2-propanol, melting point 95.5 ℃. |
WGK Germany | 3 |
purpose | cholinergic drug. Is a selective muscarinic M-1 receptor agonist. |
production method | S2Cl2 is dissolved in dimethylformamide, α-amino -α-3-pyridyl acetonitrile is added, and reaction is carried out to obtain compound (II). Reaction with sodium hexanol to obtain compound (III), and then with methyl iodide to form pyridine (IV), and finally with sodium borohydride reduction to obtain the product. |