XL413
XL413
CAS: 1169562-71-3
Molecular Formula: C14H13Cl2N3O2
XL413 - Names and Identifiers
XL413 - Physico-chemical Properties
| Molecular Formula | C14H13Cl2N3O2 |
| Molar Mass | 326.17792 |
| Appearance | powder |
| Color | white to beige |
| Storage Condition | -20°C |
| In vitro study | In MDA-MB-231T and Colo-205 cell lines, XL413 inhibits MCM2 cdc7-specific phosphorylation. XL413 also inhibits cell proliferation in Colo-205 cells, reduces cell viability, and elicits caspase 3/7 activity. In addition, XL413 causes S-phase progression to be altered, which subsequently causes apoptosis. |
| In vivo study | In the Colo-205 xenograft model, XL413, at a dose of 3 mg/kg, inhibited 70% of the phosphorylated MCM2 and caused significant tumor growth regression at a dose of 100 mg/kg. |
XL413 - Risk and Safety
| UN IDs | UN 2811 6.1 / PGIII |
XL413 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.066 ml | 15.329 ml | 30.658 ml |
| 5 mM | 0.613 ml | 3.066 ml | 6.132 ml |
| 10 mM | 0.307 ml | 1.533 ml | 3.066 ml |
| 5 mM | 0.061 ml | 0.307 ml | 0.613 ml |
Last Update：2024-01-02 23:10:35
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Spot supply
Product Name: XL413 Visit Supplier Webpage Request for quotationCAS: 1169562-71-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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