Z-Glu(OBzl)-OH

Z-Glu(OBzl)-OH - Names and Identifiers

Name	Z-Glu(OBzl)-OH
Synonyms	Z-Glu(OBzl)-OH Z-GLU(OBZL)-OH Z-L-GLU(BZL)-OH N-a-CBZ-(g-OBzl)-D-Glu Z-GLUTAMIC ACID(OBZL)-OH Z-Glutamic Acid-O Benzyl Ester Cbz-L-glutamic acid 5-benzyl ester Cbz-L-Glutamic Acid-r-Benyzl Ester Z-L-GLUTAMIC ACID GAMMA-BENZYL ESTER N-CBZ-L-Glutamic Acid Gamma-Benzyl Ester N-ALPHA-CBZ-L-GLUTAMIC ACID GAMMA-BENZYL ESTER N-BENZYLOXYCARBONYL-L-GLUTAMIC ACID GAMMA-BENZYL ESTER N-ALPHA-CARBOBENZOXY-L-GLUTAMIC ACID GAMMA-BENZYL ESTER (s)-2-benzyloxycarbonylamino-pentanedioic acid 5-benzyl ester (S)-2-Benzyloxycarbonylamino-pentanedioic acid 5-benzyl ester 5-(benzyloxy)-2-{[(benzyloxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name) (2S)-5-(benzyloxy)-2-{[(benzyloxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name)
CAS	5680-86-4
EINECS	611-426-7
InChI	InChI=1/C20H21NO6/c22-18(26-13-15-7-3-1-4-8-15)12-11-17(19(23)24)21-20(25)27-14-16-9-5-2-6-10-16/h1-10,17H,11-14H2,(H,21,25)(H,23,24)/t17-/m0/s1

Z-Glu(OBzl)-OH - Physico-chemical Properties

Molecular Formula	C20H21NO6
Molar Mass	371.38
Density	1.268±0.06 g/cm3(Predicted)
Melting Point	74.0 to 78.0 °C
Boling Point	594.3±50.0 °C(Predicted)
Flash Point	313.2°C
Water Solubility	Soluble in ethanol. Insoluble in water.
Vapor Presure	5.72E-15mmHg at 25°C
Appearance	powder to crystal
Color	White to Almost white
pKa	3.79±0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.575

Z-Glu(OBzl)-OH - Risk and Safety

HS Code

29224290

Z-Glu(OBzl)-OH - Introduction

Z-Glu(OBzl)-OH(Z-Glu(OBzl)-OH) is an organic compound with the following properties:

1. Appearance: generally white crystalline solid;
2. molecular formula: C21H21NO6;
3. Molecular weight: 383.39g/mol;
4. Melting point: about 125-130°C.

It is a derivative of glutamic acid with certain chemical reactivity and is commonly used in organic synthesis reactions.

Use:
Z-Glu(OBzl)-OH is often used as a protecting group or as an intermediate compound. In organic synthesis, it can be selectively deprotected to restore the activity of glutamic acid, or used as a protected group for the synthesis of other complex organic compounds. It has a wide range of applications in the synthesis of peptides, polypeptides and other bioactive molecules.

Preparation Method:
The preparation of Z-Glu(OBzl)-OH is usually carried out by chemical synthesis methods. Glutamic acid first reacts with benzyl alcohol to generate benzyloxycarbonyl-glutamic acid gamma benzyl ester, and then the ester protecting group is removed by hydrolysis or other means to obtain the final product Z-Glu(OBzl)-OH.

Safety Information:
Since Z-Glu(OBzl)-OH is an organic compound, it may be toxic to the human body. During use and handling, it is necessary to comply with laboratory safety procedures, including wearing protective gloves, glasses and laboratory coats, and ensuring that the operating fan is well ventilated. In addition, the storage of chemicals also needs to be handled carefully to avoid contact with incompatible substances such as oxidants and combustibles.

Last Update：2024-04-10 22:29:15