Z-N-DELTA-TRITYL-L-GLUTAMINE
Z-Gln(Trt)-OH
CAS: 132388-60-4
Molecular Formula: C32H30N2O5
Z-N-DELTA-TRITYL-L-GLUTAMINE - Names and Identifiers
| Name | Z-Gln(Trt)-OH |
| Synonyms | Z-GLN(TRT)-OH Z-Gln(Trt)-OH CBZ-GLN(TRT)-OH Z-GLUTAMINE(TRT)-OH Z-L-GLUTAMINE (TRITYL) CBZ-L-GLUTAMINE(TRITYL) Z-N-DELTA-TRITYL-L-GLUTAMINE N-ALPHA-CBZ-GAMMA-TRITYL-L-GLUTAMINE N-ALPHA-CARBOBENZOXY-N-GAMMA-TRITYL-L-GLUTAMINE N~2~-[(benzyloxy)carbonyl]-N-trityl-L-glutamine |
| CAS | 132388-60-4 |
| InChI | InChI=1/C32H30N2O5/c35-29(22-21-28(30(36)37)33-31(38)39-23-24-13-5-1-6-14-24)34-32(25-15-7-2-8-16-25,26-17-9-3-10-18-26)27-19-11-4-12-20-27/h1-20,28H,21-23H2,(H,33,38)(H,34,35)(H,36,37)/t28-/m0/s1 |
Z-N-DELTA-TRITYL-L-GLUTAMINE - Physico-chemical Properties
| Molecular Formula | C32H30N2O5 |
| Molar Mass | 522.59 |
| Density | 1.237±0.06 g/cm3(Predicted) |
| Melting Point | 160-1650℃ |
| Boling Point | 792.6±60.0 °C(Predicted) |
| Flash Point | 433.175°C |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | White powder |
| pKa | 3.82±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.613 |
Z-N-DELTA-TRITYL-L-GLUTAMINE - Introduction
N-Cbz-N '-Trityl-L-glutamine is an organic compound with the following properties:
1. properties: N-Cbz-N '-trityl-L-glutamine is a white solid, with good solubility, soluble in polar organic solvents. It is a stable compound and can be stored for a long time under dry conditions.
2. use: N-Cbz-N '-trityl-L-glutamine is commonly used as a protective group in chemical synthesis, which can protect the amino (-NH2) functional group in glutamine from reaction, thus plays an important role in selective chemical reaction. In addition, it can also be used as a precursor molecule in drug synthesis.
3. Preparation method: The preparation of N-Cbz-N-trityl-L-glutamine is usually obtained by reacting L-glutamine with benzoyl chloride. The reaction is generally carried out under inert atmosphere and low temperature conditions. Subsequently, trityl amine can be reacted with the formed benzamide to yield the N-Cbz-N '-trityl-L-glutamine product.
4. Safety information: N-Cbz-N '-Trityl-L-glutamine is less dangerous under normal operating conditions. However, it is still an organic compound that needs to be handled and stored correctly in the laboratory. Inhalation or contact with skin and eyes should be avoided. Wear appropriate personal protective equipment such as lab gloves and safety glasses during use.
1. properties: N-Cbz-N '-trityl-L-glutamine is a white solid, with good solubility, soluble in polar organic solvents. It is a stable compound and can be stored for a long time under dry conditions.
2. use: N-Cbz-N '-trityl-L-glutamine is commonly used as a protective group in chemical synthesis, which can protect the amino (-NH2) functional group in glutamine from reaction, thus plays an important role in selective chemical reaction. In addition, it can also be used as a precursor molecule in drug synthesis.
3. Preparation method: The preparation of N-Cbz-N-trityl-L-glutamine is usually obtained by reacting L-glutamine with benzoyl chloride. The reaction is generally carried out under inert atmosphere and low temperature conditions. Subsequently, trityl amine can be reacted with the formed benzamide to yield the N-Cbz-N '-trityl-L-glutamine product.
4. Safety information: N-Cbz-N '-Trityl-L-glutamine is less dangerous under normal operating conditions. However, it is still an organic compound that needs to be handled and stored correctly in the laboratory. Inhalation or contact with skin and eyes should be avoided. Wear appropriate personal protective equipment such as lab gloves and safety glasses during use.
Last Update：2024-04-09 20:45:29
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