ZD-6

ZD-6 - Names and Identifiers

Name	Methyl (+)-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino)pyrimidin-5-yl]-3-hydroxy-5-oxo-(6E)-heptenoate
Synonyms	H-2 ZD-6 5-Oxorosuvastatin Methyl ester (R,E)-Methyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)-pyrimidin-5-yl)-3-hy Methyl(+)-(3-R)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-(N-Methyl-N-Methanesul fonylaMino) pyriMidin-5-y (R,E)-Methyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-MethylMethylsulfonaMido)pyriMidin-5-yl)-3-hydroxy-5-oxohept-6-enoate Methyl 7-[4-(4-FLUOROPHENYL)-6-ISO-PROPYL-2-(N-METHYL-N-METHYLSULFONYLAMINO)PYRIMIDIN-5-YL] -(3R,5R)-DIHYDROXY-(E)-6-HEPTENATE Methyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R)-3-hydroxy-5-oxo-(E)-6-heptenate methyl (3R,6E)-7-{4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3-hydroxy-5-oxohept-6-enoate Methyl (+)-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-Methyl-NMethansulphonylaMino)pyriMidin-5-yl]-3-hydroxy-5-oxo-6(E)-heptenoate Methyl (+)-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino)pyrimidin-5-yl]-3-hydroxy-5-oxo-(6E)-heptenoate Methyl(+)-(3-R)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino) pyrimidin-5-yl]-3-hydroxy-5-oxo-6(E)-heptenoate Methyl-(+)-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-(methansulphonyl amino)pyrimidin-5-yl]-3-hydroxy-5-oxo-6(E)-heptenoate Methyl(+)-(3-R)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesul fonylamino) pyrimidin-5-yl]-3-hydroxy-5-oxo-6(E)-heptenoate (3R,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3-hydroxy-5-oxo-6-heptenoic acid methyl ester
CAS	147118-39-6
EINECS	604-567-0
InChI	InChI=1/C23H28FN3O6S/c1-14(2)21-19(11-10-17(28)12-18(29)13-20(30)33-4)22(15-6-8-16(24)9-7-15)26-23(25-21)27(3)34(5,31)32/h6-11,14,18,29H,12-13H2,1-5H3/b11-10+/t18-/m1/s1

ZD-6 - Physico-chemical Properties

Molecular Formula	C23H28FN3O6S
Molar Mass	493.55
Density	1.311
Melting Point	103-107°C
Boling Point	701.7±70.0 °C(Predicted)
Flash Point	378.2°C
Solubility	DMSO (Slightly), Methanol (Slightly)
Vapor Presure	1.15E-20mmHg at 25°C
Appearance	Solid
Color	Pale Yellow to Yellow
pKa	12.87±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.569

ZD-6 - Introduction

Methyl ( )-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino)pyrimidin-5-yl]-3-hydroxy-5-oxo-(6E)-heptenoate, it has the following properties, uses, methods and safety information:

Nature:
-Appearance: A compound is a colorless to pale yellow liquid.
-Molecular formula: C22H23FN4O5S
-Melting point: no clear data
-Boiling point: no clear data
-Solubility: A compound has good solubility in common organic solvents.

Use:
A compound is often used as a pharmaceutical intermediate, especially in the field of anti-inflammatory, anti-tumor and immune regulation.

Method:
The preparation of a compound generally includes the following steps:
1. Synthesis of representative intermediates by chemical reaction.
2. The intermediate is subjected to a protective group formation reaction to modify its structure.
3. The desired functional group is introduced into the specific position of the intermediate through different reaction steps.
4. A compound is finally obtained.

Safety Information:
-Precise toxicity data for a compound is lacking. However, as a chemical substance, appropriate safety measures should be taken when handling and using, such as wearing protective gloves, eye protection equipment and respiratory protection.
-When using a certain compound for experiments, it should be operated in a well-ventilated laboratory and follow correct laboratory operating procedures and safe operating guidelines.
-If you ingest or come into contact with a compound, seek medical attention immediately and provide your doctor with detailed information about the compound.

Last Update：2024-04-09 20:45:29