Zinc,chloro(2-pyridiylmethyl)-
2-Pyridinylmethyl zinc chloride
CAS: 165334-81-6
Molecular Formula: C6H6ClNZn
Zinc,chloro(2-pyridiylmethyl)- - Names and Identifiers
| Name | 2-Pyridinylmethyl zinc chloride |
| Synonyms | Zinc,chloro(2-pyridiylmethyl)- 2-Pyridinylmethyl zinc chloride 2-Pyridinylmethylzinc chloride 0.5 M in Tetrahydrofuran |
| CAS | 165334-81-6 |
Zinc,chloro(2-pyridiylmethyl)- - Physico-chemical Properties
| Molecular Formula | C6H6ClNZn |
| Molar Mass | 192.96154 |
Zinc,chloro(2-pyridiylmethyl)- - Introduction
2-Pyridinylmethyl zinc chloride is an organic zinc compound with the chemical formula C6H7Cl2N2Zn. It is a white solid and relatively stable in air.
2-Pyridinylmethyl zinc chloride is widely used in organic synthesis. It is a useful reagent for catalyzing the formation of C- C bonds and the construction of carbon-nitrogen bonds. It can be used to prepare metal organic reagents of compounds, such as Grignard reagents and organozinc reagents. In addition, 2-Pyridinylmethyl zinc chloride can also be used as reagents and catalysts in organic synthesis for various reactions, such as addition, indole, hydrogenation, substitution and reduction reactions.
2-Pyridinylmethyl zinc chloride can be prepared by reacting 2-bromomethylpyridine with zinc powder. The reaction may be carried out in an anhydrous solvent and promoted by heating. Usually, zinc chloride is added to the reaction system as a catalyst. During the reaction, 2-bromomethylpyridine is reduced by zinc to give 2-Pyridinylmethyl zinc chloride.
Regarding safety information, 2-Pyridinylmethyl zinc chloride should be stored under dark, low temperature and dry conditions. When handling, wear appropriate personal protective equipment such as gloves and protective glasses. At the same time, avoid contact with skin, eyes and respiratory tract. In case of contact, rinse immediately with plenty of water and seek medical help.
2-Pyridinylmethyl zinc chloride is widely used in organic synthesis. It is a useful reagent for catalyzing the formation of C- C bonds and the construction of carbon-nitrogen bonds. It can be used to prepare metal organic reagents of compounds, such as Grignard reagents and organozinc reagents. In addition, 2-Pyridinylmethyl zinc chloride can also be used as reagents and catalysts in organic synthesis for various reactions, such as addition, indole, hydrogenation, substitution and reduction reactions.
2-Pyridinylmethyl zinc chloride can be prepared by reacting 2-bromomethylpyridine with zinc powder. The reaction may be carried out in an anhydrous solvent and promoted by heating. Usually, zinc chloride is added to the reaction system as a catalyst. During the reaction, 2-bromomethylpyridine is reduced by zinc to give 2-Pyridinylmethyl zinc chloride.
Regarding safety information, 2-Pyridinylmethyl zinc chloride should be stored under dark, low temperature and dry conditions. When handling, wear appropriate personal protective equipment such as gloves and protective glasses. At the same time, avoid contact with skin, eyes and respiratory tract. In case of contact, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-10 22:29:15
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Email: biz5@infsci.com
Mobile: 15001012717
QQ: 3007471201
Product List: View Catalog
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