Zinc02563779

Zinc02563779 - Names and Identifiers

Name	3-Iodo-5-Methoxyindole-1-Carboxylic Acid Tert-Butyl Ester
Synonyms	Zinc02563779 3-Iodo-5-methoxyindole, N-BOC protected 3-Iodo-5-Methoxyindole, N-Boc Protected tert-butyl 3-iodo-5-Methoxy-1H-indole-1-carboxylate tert-butyl 3-iodo-5-methoxy-1H-indole-1-carboxylate 3-Iodo-5-Methoxyindole-1-Carboxylic Acid Tert-Butyl Ester 3-IODO-5-METHOXYINDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 3-Iodo-5-methoxy-1H-indole-1-carboxylic acid tert-butyl ester 1H-Indole-1-carboxylicacid, 3-iodo-5-methoxy-, 1,1-dimethylethylester 1H-Indole-1-carboxylic acid, 3-iodo-5-Methoxy-, 1,1-diMethylethyl ester
CAS	192189-10-9
InChI	InChI=1/C14H16INO3/c1-14(2,3)19-13(17)16-8-11(15)10-7-9(18-4)5-6-12(10)16/h5-8H,1-4H3

Zinc02563779 - Physico-chemical Properties

Molecular Formula	C14H16INO3
Molar Mass	373.19
Density	1.545g/cm³
Boling Point	423.312°C at 760 mmHg
Flash Point	209.812°C
Vapor Presure	0mmHg at 25°C
Storage Condition	2-8°C(protect from light)
Refractive Index	1.594

Zinc02563779 - Risk and Safety

Hazard Note

Harmful

Zinc02563779 - Introduction

Acid Tert-Butyl Ester, chemical formula C13H15INO3, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
1. Appearance: Acid Tert-Butyl Ester is a white or off-white crystalline powder.
2. Melting Point: about 85-90 ℃.
3. Solubility: Acid Tert-Butyl Ester is soluble in alcohol and ether solvents, but insoluble in water.

Use:
Acid Tert-Butyl Ester has certain application value in the field of medicine. It can be used as an intermediate of anti-cancer drugs and used in the synthesis of nitroso oligo-indole analogs. In addition, it is also used for catalytic reactions in organic synthesis.

Method:
The preparation method of Acid Tert-Butyl Ester is more complicated, and it is usually synthesized through a multi-step reaction. A common method is to react 3-iodoindole with methanol and alkylene alcohol in the presence of an acidic catalyst to give 3-iodo-5-methoxyindole. Subsequently, the product was reacted with acetonitrile, trifluoromethylpyruvate, etc., and then through the steps of reduction and acylation, the acidester Tert-Butyl was finally obtained.

Safety Information:
1. Acid Tert-Butyl Ester is an organic compound. Attention should be paid to protective measures during use and operation to avoid contact with skin and mucous membranes.
2. In the storage and handling of the compound, should be away from the fire and oxidant, to avoid fire or explosion accident.
3. Operation process should use appropriate ventilation equipment to ensure indoor air circulation, avoid harmful gas accumulation.
4. When there are discomfort symptoms caused by contact or inhalation of the compound, stop the operation immediately and seek medical attention in time.

Last Update：2024-04-09 20:52:54