Molecular Formula | C10H6ClNO2 |
Molar Mass | 207.61 |
Density | 1.49 |
Melting Point | 198-200 °C |
Boling Point | 310℃ |
Flash Point | 141℃ |
Water Solubility | Insoluble in water |
Vapor Presure | 0.000608mmHg at 25°C |
Appearance | Solid |
Color | Orange |
pKa | 0.70±0.20(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.5790 (estimate) |
MDL | MFCD00001680 |
Physical and Chemical Properties | Melting Point: 198-200°C storage conditions: 0-6°C |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R23 - Toxic by inhalation R22 - Harmful if swallowed R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R36 - Irritating to the eyes |
Safety Description | S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S60 - This material and its container must be disposed of as hazardous waste. |
UN IDs | UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all |
WGK Germany | 3 |
RTECS | QL7350000 |
HS Code | 29223990 |
Hazard Class | 6.1 |
Toxicity | LD50 oral in rat: 1360mg/kg |
Plant source: | Ginkgo biloba |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
Biological activity | Quinoclamine is a naphthoquinone derivative and an NF-κB inhibitor. Quinoclamine has anti-tumor activity. |
Target | NF-κB |
Cell Line: | HepG2 cells HepG2 cells |
Concentration: | 1 μM, 2 μM, 4 μM, 8 μM, 16 μM, 32 μM, 64 μM 0 μM, 1 μM, 2 μM, 4 μM |
Incubation Time: | 24 hours 30 minutes |
Result: | Inhibited NF-κB activities in HepG2 cells. Inhibited IκB-α phosphorylation and p65 translocation in HepG2 cells. |
category | pesticide |
toxicity classification | poisoning |
acute toxicity | oral-rat LD50: 1360 mg/kg; Oral-mouse LD50: 1260 mg/kg |
flammability hazard characteristics | Combustion produces toxic nitrogen oxides and chloride gases |
storage and transportation characteristics | warehouse ventilation and low temperature drying; separate from food raw materials storage and transportation |
fire extinguishing agent | dry powder, foam, sand |