alpha-d-galactopyranoside,4-nitrophenyl
p-nitrophenyl α-D-galactopyranoside
CAS: 7493-95-0
Molecular Formula: C12H15NO8
alpha-d-galactopyranoside,4-nitrophenyl - Names and Identifiers
| Name | p-nitrophenyl α-D-galactopyranoside |
| Synonyms | PNPG 231-343-6 PNP-ALPHA-GAL PNP-ALPHA-D-GAL PNP ALPHA-D-GALACTOPYRANOSIDE p-nitrophenyl α-D-galactopyranoside P-NITROPHENYL A-D-GALACTOPYRANOSIDE P-NITROPHENYL ALPHA-D-GALACTOPYRANOSIDE 4-NITROPHENYL-ALPHA-D-GALACTOPYRANOSIDE 4-nitrophenyl alpha-D-galactopyranoside 4-Nitrophenyl-Alpha-D-Galactopyranoside alpha-d-galactopyranoside,4-nitrophenyl alpha-D-Galactopyranoside, 4-nitrophenyl p-Nitrophenyl .alpha.-D-galactopyranoside .alpha.-D-Galactopyranoside, 4-nitrophenyl |
| CAS | 7493-95-0 |
| EINECS | 231-343-6 |
| InChI | InChI=1/C12H15NO8/c14-5-8-9(15)10(16)11(17)12(21-8)20-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8-,9+,10+,11-,12+/m1/s1 |
| InChIKey | IFBHRQDFSNCLOZ-IIRVCBMXSA-N |
alpha-d-galactopyranoside,4-nitrophenyl - Physico-chemical Properties
| Molecular Formula | C12H15NO8 |
| Molar Mass | 301.25 |
| Density | 1.599±0.06 g/cm3(Predicted) |
| Melting Point | 166-169°C |
| Boling Point | 582.2±50.0 °C(Predicted) |
| Specific Rotation(α) | 239 ° (C=1, H2O) |
| Flash Point | 305.9°C |
| Solubility | Methanol (Slightly), Water (Slightly) |
| Vapor Presure | 2.14E-14mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White |
| BRN | 92214 |
| pKa | 12.55±0.70(Predicted) |
| Storage Condition | -20°C |
| Sensitive | Easily absorbing moisture |
| Refractive Index | 239 ° (C=1, H2O) |
| MDL | MFCD00065050 |
| Use | Substrate of α-D-galactosidase (α-D-Galactosidase) |
| In vitro study | Using 4-nitorophenol (pNP)-glycopyranosides as pseudosubstrates, the amount of liberated pNP from the 4-Nitrophenyl α-D-galactopyranoside is significantly higher than that from the other pNP-glycopyranosides at pH 4.0 whereas no activity was detected at pH 7.0. The digestion assays using 4-nitrophenyl (pNP) glycopyranosides as artificial substrates shows that yieldin liberated galactose residues from 4-Nitrophenyl α-D-galactopyranoside mainly at pH 4.0, i.e. the pH level where yield threshold is decreased at most. |
alpha-d-galactopyranoside,4-nitrophenyl - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 3-10-21 |
| HS Code | 29400090 |
alpha-d-galactopyranoside,4-nitrophenyl - Reference
| Reference Show more | 1. Li Hui, Li Jie, Wang Qingzhang, et al. Effects of Air discharge on Fusarium M4 and its infection activity in postharvest lotus root [J]. Chinese Journal of Food Science, 2015, 15(10):58-64. 2. [IF = 7.514] Jiangtao Zhang et al."Chemical compositions and alpha-glucosidase inhibitory effects of anthocyanidins from blue, blackcurrant and blue honey fruit." Food Chem. 2019 Nov;299:125102 3. [IF = 3.493] Jie Zhang et al."Exploring the catalytic mechanism of a novel β-glucosidase BGL0224 from oenoccus oenib SD-2a, spectroscopic and molecular simulation."Enzyme Microb Tech. 2021 Aug;148:109814 4. [IF=3.205] Xiaorong Hou et al."Development of an immobilized liposome chromatography method for screening and characterizing α-glucosidase-binding compounds."J Chromatogr B. 2020 Jul;1148:122097 5. [IF=2.104] Jianhua Xie et al."A thermophilic fungal GH36 α-galactosidase from Lichtheimia ramosa and its synergistic hydrolysis of locust bean gum."Carbohyd Res. 2020 May;491:107911 6. [IF=5.64] Xingyu Zhai et al."Structure and Function Insight of the α-Glucosidase QsGH13 From Qipengyuania seohaensis sp. SW-135.."Front Microbiol. 2022 Mar;13:849585-849585 |
alpha-d-galactopyranoside,4-nitrophenyl - Reference Information
| biological activity | 4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is a 4-Nitrophenyl (pNP) artificial substrate for glycosopyranoside for the detection of α-galactosidase activity. When 4-Nitrophenyl alpha-d-galactopyranoside is used as a substrate, the amount of released pNP is significantly increased. |
| Use | a substrate for α-D-galactosidase. Binding to E. Coli lactose protein carrier. Α-D-milk sugar medium |
Last Update：2024-04-09 21:01:54
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