anthranilicacid,phenethylester
Phenylethyl Anthranilate
CAS: 133-18-6
Molecular Formula: C15H15NO2
anthranilicacid,phenethylester - Names and Identifiers
anthranilicacid,phenethylester - Physico-chemical Properties
| Molecular Formula | C15H15NO2 |
| Molar Mass | 241.29 |
| Density | 1.0944 (rough estimate) |
| Melting Point | 39-44°C(lit.) |
| Boling Point | 226°C(lit.) |
| FEMA | 2859 | PHENYLETHYL ANTHRANILATE |
| Flash Point | >230°F |
| JECFA Number | 1543 |
| Color | White to yellow crystals |
| Odor | grape odor |
| Refractive Index | 1.5200 (estimate) |
| Physical and Chemical Properties | Colorless to light yellow crystals. Orange flower-like aroma and grape fragrance. Boiling point 324 °c. Soluble in ethanol. |
anthranilicacid,phenethylester - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 3077 9/PG 3 |
| WGK Germany | 2 |
| RTECS | CB3720000 |
| Toxicity | skn-rbt 500 mg/24H MOD FCTXAV 14,659,76 |
anthranilicacid,phenethylester - Introduction
Phenylethyl Anthranilate, also known as N-benzyl-N-phenylformamide or Benzocaine, is an organic compound. The following is a description of its nature, use, preparation and safety information:
1. Nature:
-Appearance: white crystalline powder or crystalline flake
-Solubility: Soluble in organic solvents, insoluble in water
-Melting Point: about 89-92 ℃
-molecular formula: C9H11NO2
-Molecular weight: 165.19g/mol
2. Use:
-Anesthetic: Phenylethyl Anthranilate is a local anesthetic commonly used to reduce pain and itching in the skin or mucous membranes. It is often used in the medical, dental, and cosmetic fields as a topical anesthetic or ingredient in oral preparations.
-Drug intermediate: It can also be used as a synthetic intermediate for certain drugs and used to prepare other drugs and compounds.
-Cosmetics: Due to its analgesic and anti-infection properties, Phenylethyl Anthranilate is also often used as an ingredient in cosmetics, such as mouth rinses, toothpastes, etc.
3. Preparation method:
Phenylethyl Anthranilate is usually prepared by reacting 2-amino-benzoic acid with 2-phenylethanol. Wherein, 2-amino-benzoic acid and 2-phenylethanol in the presence of a catalyst (such as sodium hydroxide), esterification reaction can be carried out to produce target product.
4. Safety Information:
- Phenylethyl Anthranilate is generally considered to be a relatively safe compound, but it is still necessary to follow safe procedures for use and storage.
-When exposed to Phenylethyl Anthranilate, take necessary personal protective measures, such as wearing protective gloves and goggles.
-Avoid inhaling powder or solution, and operate in a well-ventilated place.
-If ingested or inhaled, seek medical attention immediately and provide relevant chemical and safety information.
1. Nature:
-Appearance: white crystalline powder or crystalline flake
-Solubility: Soluble in organic solvents, insoluble in water
-Melting Point: about 89-92 ℃
-molecular formula: C9H11NO2
-Molecular weight: 165.19g/mol
2. Use:
-Anesthetic: Phenylethyl Anthranilate is a local anesthetic commonly used to reduce pain and itching in the skin or mucous membranes. It is often used in the medical, dental, and cosmetic fields as a topical anesthetic or ingredient in oral preparations.
-Drug intermediate: It can also be used as a synthetic intermediate for certain drugs and used to prepare other drugs and compounds.
-Cosmetics: Due to its analgesic and anti-infection properties, Phenylethyl Anthranilate is also often used as an ingredient in cosmetics, such as mouth rinses, toothpastes, etc.
3. Preparation method:
Phenylethyl Anthranilate is usually prepared by reacting 2-amino-benzoic acid with 2-phenylethanol. Wherein, 2-amino-benzoic acid and 2-phenylethanol in the presence of a catalyst (such as sodium hydroxide), esterification reaction can be carried out to produce target product.
4. Safety Information:
- Phenylethyl Anthranilate is generally considered to be a relatively safe compound, but it is still necessary to follow safe procedures for use and storage.
-When exposed to Phenylethyl Anthranilate, take necessary personal protective measures, such as wearing protective gloves and goggles.
-Avoid inhaling powder or solution, and operate in a well-ventilated place.
-If ingested or inhaled, seek medical attention immediately and provide relevant chemical and safety information.
Last Update：2024-04-09 01:59:55
