Name | Armepavine |
Synonyms | Armepavine R-Armepavine (-)-Armepavine Phenol, 4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]- |
CAS | 524-20-9 |
Molecular Formula | C19H23NO3 |
Molar Mass | 313.39 |
Density | 1.151±0.06 g/cm3(Predicted) |
Melting Point | 149-150° |
Boling Point | 460.5±45.0 °C(Predicted) |
Specific Rotation(α) | D20 -117.6° (CHCl3) (Knabe); D27 -103.2° (Farber) |
pKa | 9.99±0.15(Predicted) |
Storage Condition | 2-8°C,密封,干燥 |
biological activity | Armepavine, an active compound from Nelumbo nucifera, not only has anti-inflammatory effects on human peripheral blood mononuclear cells, it also has immunosuppressive effect on T lymphocytes and lupus nephritis mice. Armepavine inhibits TNF-α-induced MAPK and NF-κB signaling cascades. |