Name | Arteether |
Synonyms | Arteether arteether beta-Artether 10-ethoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene 10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin 10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin 3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl- (3R,5aS,6R,8aS,9R,12R,12aR)-10-ethoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene (5aS,6R,8aS,9R,10S,12R,12aR)-10-ethoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene |
CAS | 109716-83-8 131175-88-7 75887-54-6 |
InChI | InChI=1/C17H28O5/c1-5-18-14-11(3)13-7-6-10(2)12-8-9-16(4)20-15(19-14)17(12,13)22-21-16/h10-15H,5-9H2,1-4H3/t10-,11-,12+,13+,14?,15-,16-,17-/m1/s1 |
Molecular Formula | C17H28O5 |
Density | 1.16g/cm3 |
Melting Point | 80-820 °C |
Boling Point | 372.4°C at 760 mmHg |
Specific Rotation(α) | D21 +154.5° (c = 1.0 in CHCl3) |
Flash Point | 146°C |
Solubility | Soluble in DMSO |
Vapor Presure | 2.06E-05mmHg at 25°C |
Appearance | White crystalline solid |
Storage Condition | 2-8℃ |
Refractive Index | 1.516 |
MDL | MFCD00869355 |
with dehydrated dihydroartemisinin and ethanol, in triphenylphosphine hydrogen bromide complex catalyzed reaction of artemether.
developed by Brocacef, Inc., the Netherlands, was first launched in 2000 in the Netherlands. DNA synthesis inhibitors, semi-synthetic artemisinin derivatives, intramuscular injection with antimalarial drugs. For the treatment of various types of malaria. Can also be used for acute Upper Respiratory Infections of patients with high fever, antipyretic effect of stability. The asexual body of Plasmodium has a strong killing effect, can quickly control the symptoms.