azido-PEG5-OH
14-Azido-3,6,9,12-tetraoxatetradecanol
CAS: 86770-68-5
Molecular Formula: C12H25N3O7
azido-PEG5-OH - Names and Identifiers
azido-PEG5-OH - Physico-chemical Properties
| Molecular Formula | C12H25N3O7 |
| Molar Mass | 323.3428 |
| Flash Point | 100℃ |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Appearance | Colorless-yellow transparent liquid |
| Color | Clear Colourless |
| Storage Condition | 0-10°C |
| Refractive Index | 1.4650-1.4690 |
| MDL | MFCD20134131 |
| In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
azido-PEG5-OH - Risk and Safety
| HS Code | 29051990 |
azido-PEG5-OH - Reference Information
| use | 14-azide -3,6,9,12-tetraoxetanol is a polyethylene glycol (PEG) derivative used to prepare various targeted microenvironment sensors. |
| biological activity | Azido-PEG5-alcohol is a non-cleavable ADC linker containing 5 unit PEG, which can be used to synthesize antibody-coupled drugs (ADC). Azido-PEG5-alcohol is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules. |
| target | PEGs Non-cleavable |
| in vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Last Update：2024-04-09 19:05:04
