Name | phenformin |
Synonyms | azucaps beta-PEBG phenformin cronoformin 1-phenethyl-biguanid 1-phenethylbiguanide beta-Phenethybiguanide (phenylethyl)biguanide Biguanide, 1-phenethyl- beta-Phenethylbiguanide 1-(diaminomethylidene)-2-(2-phenylethyl)guanidine |
CAS | 114-86-3 |
EINECS | 204-057-4 |
InChI | InChI=1/C10H15N5/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H6,11,12,13,14,15) |
Molecular Formula | C10H15N5 |
Molar Mass | 205.26 |
Density | 1.0541 (rough estimate) |
Melting Point | 176.5 °C |
Boling Point | 333.94°C (rough estimate) |
Flash Point | 204°C |
Vapor Presure | 4.71E-07mmHg at 25°C |
pKa | pKa 3.1/12.9±0.01(H2O,t =25,I>0.1) (Uncertain) |
Refractive Index | 1.6380 (estimate) |
Physical and Chemical Properties | Its hydrochloride is commonly used. White crystalline powder. Soluble in water. Dissolved in ethanol, almost insoluble in chloroform or ether. |
Use | Can reduce liver sugar decomposition and promote muscle sugar synthesis, thereby reducing blood sugar. For the treatment of adult non-insulin-dependent diabetes mellitus and part of insulin-dependent diabetes mellitus. |
Hazard Symbols | Xn - Harmful |
Risk Codes | 22 - Harmful if swallowed |
Safety Description | 36 - Wear suitable protective clothing. |
WGK Germany | 3 |
RTECS | DU2200000 |
Toxicity | LD50 orl-rat: 1650 mg/kg BCFAAI 110,470,71 |