bafetinib
Bafetinib
CAS: 887650-05-7;859217-05-3;859212-16-1
Molecular Formula: C30H31F3N8O
bafetinib - Names and Identifiers
| Name | Bafetinib |
| Synonyms | Lyn-IN-1 bafetinib Bafetinib Bafetinib analog (S)-N-(3-(5,5'-Bipyrimidin-2-ylamino)-4-methylphenyl)-4-((3-(dimethylamino)-pyrrolidin-1-yl)me (S)-N-(3-([5,5'-bipyriMidin]-2-ylaMino)-4-Methylphenyl)-4-((3-(diMethylaMino)pyrrolidin-1-yl)Methyl)-3-(trifluoroMethyl)benzaMide N-[3-([5,5'-Bipyrimidin]-2-ylamino)-4-methylphenyl]-4-[[(3S)-3-(dimethylamino)-1-pyrrolidinyl]methyl]-3-(trifluoromethyl)benzamide N-{3-[([5,5'-bipyrimidin]-2-yl)amino]-4-methylphenyl}-4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]methyl}-3-(trifluoromethyl)benzamide Benzamide, N-[3-([5,5'-bipyrimidin]-2-ylamino)-4-methylphenyl]-4-[[(3S)-3-(dimethylamino)-1-pyrrolidinyl]methyl]-3-(trifluoromethyl)- |
| CAS | 887650-05-7 859217-05-3 859212-16-1 |
| EINECS | 1312995-182-4 |
bafetinib - Physico-chemical Properties
| Molecular Formula | C30H31F3N8O |
| Molar Mass | 576.62 |
| Density | 1.36 |
| Melting Point | >166°C (dec.) |
| Solubility | DMSO, Methanol |
| Appearance | Solid |
| Color | Yellow |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Physical and Chemical Properties | Appearance: white or white-like crystalline powder Dissolution: dissolved in DMSO (up to 100 mM) Preservation: 3 years -20 ℃ powder Figure 1 shows bafitinib |
| Use | Bafetinib (INNO-406) is an effective, selective, Bcr-Abl/Lyn dual inhibitor with IC50 of 5.8 nM/19 nM. It has no inhibitory effect on phosphorylation of T315I mutant, and has a slightly weaker effect on PDGFR and c-Kit. |
bafetinib - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.734 ml | 8.671 ml | 17.342 ml |
| 5 mM | 0.347 ml | 1.734 ml | 3.468 ml |
| 10 mM | 0.173 ml | 0.867 ml | 1.734 ml |
| 5 mM | 0.035 ml | 0.173 ml | 0.347 ml |
Last Update：2024-01-02 23:10:35
Supplier List
Multiple SpecificationsSpot supply
Product Name: Bafetinib (INNO-406) Visit Supplier Webpage Request for quotationCAS: 859212-16-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Multiple SpecificationsSpot supply
Product Name: Bafetinib (INNO-406) Visit Supplier Webpage Request for quotationCAS: 859212-16-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History