cis-capsaicin - Names and Identifiers
cis-capsaicin - Physico-chemical Properties
Molecular Formula | C18H27NO3
|
Molar Mass | 305.41 |
Density | 1.041±0.06 g/cm3(Predicted) |
Melting Point | 70 °C |
Boling Point | 511.5±50.0 °C(Predicted) |
pKa | 9.76±0.20(Predicted) |
Storage Condition | 2-8°C |
In vitro study | (Z)-Capsaicin is the cis isomer of capsaicin, acting as a TRPV1 agonist. (Z)-Capsaicin may also blocks the neruonal calcium channel. |
In vivo study | (Z)-Capsaicin (Zucapsaicin) significantly attenuates nociceptive behavior after oral administration in rats. (Z)-Capsaicin is also tolerated in the primary or recurrent experimental genital herpes simplex virus infection in guinea pigs. |
cis-capsaicin - Risk and Safety
Toxicity | LD50 intraperitoneal in mouse: 25mg/kg |
cis-capsaicin - Reference Information
biological activity | zucapicin is a cis-isomer of capsaicin, a topical analgesic used in the treatment of knee osteoarthritis and other neuropathic pain. It is a TRPV-1 regulator. |
Target | TRPV1 receptor |
Last Update:2024-04-09 21:21:28