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cloperastine

cloperastine

CAS: 3703-76-2

Molecular Formula: C20H24ClNO

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cloperastine - Names and Identifiers

Name cloperastine
Synonyms HT 11
BRN 0275589
cloperastine
Cloperastine
CLOPERASTINE
Cloperastina
Cloperastinum
UNII-69M5L7BXEK
Cloperastine [INN]
Cloperastinum [INN-Latin]
Cloperastina [INN-Spanish]
5-20-02-00105 (Beilstein Handbook Reference)
1-[2-[p-Chloro-phenylbenzyl)-oxy]ethy]piperidine
1-(2-((4-Chlorophenyl)phenylmethoxy)ethyl)piperidine
1-(2-((4-chlorophenyl)phenylmethoxy)ethyl)-piperidin
1-(2-((4-chlorophenyl)phenylmethoxy)ethyl)piperidine
1-(2-[(4-Chlorophenyl)(phenyl)methoxy]ethyl)piperidine
1-{2-[(4-chlorophenyl)(phenyl)methoxy]ethyl}piperidine
1-(2-((p-chloro-alpha-phenylbenzyl)oxy)ethyl)-piperidin
1- 2-((p-Chloro-alpha-phenylbenzyl)oxy)ethyl piperidine
1-{2-((p-Chloro-alpha-phenylbenzyl)oxy)ethyl}piperidine
1-{2-[(p-Chloro-alpha-phenylbenzyl)oxy]ethyl}piperidine
Piperidine, 1-(2-((p-chloro-alpha-phenylbenzyl)oxy)ethyl)-
Piperidine, 1-(2-((4-chlorophenyl)phenylmethoxy)ethyl)- (9CI)
CAS 3703-76-2
EINECS 223-042-3
InChI InChI=1/C20H24ClNO/c21-19-11-9-18(10-12-19)20(17-7-3-1-4-8-17)23-16-15-22-13-5-2-6-14-22/h1,3-4,7-12,20H,2,5-6,13-16H2

cloperastine - Physico-chemical Properties

Molecular FormulaC20H24ClNO
Molar Mass329.87
Density1.0383 (rough estimate)
Boling Pointbp0.06 172-174°; bp0.15 178-180°
Flash Point210.2°C
Vapor Presure2.15E-07mmHg at 25°C
pKa8.69±0.10(Predicted)
Storage ConditionRoom Temprature
Refractive Index1.5790 (estimate)
Physical and Chemical PropertiesBoiling point 178-180 °c (20Pa),172-174 °c (8PA), its hydrochloride, C20H24CINO. HCI,Hustazol. White or off-white crystalline powder. Melting point 147.9 °c. Soluble in water, ethanol, chloroform, acetone-soluble. There was no odor, and there was numbness after the taste of octyl.
UseFor the treatment of acute upper respiratory tract inflammation, chronic bronchitis and tuberculosis caused by frequent Cough

cloperastine - Risk and Safety

ToxicityLD50 unreported in guinea pig: 439mg/kg

cloperastine - Reference

Reference
Show more
1. [IF=3.591] Meng Li et al."Chiral separation of five antihistamine drug enantiomers and enantioselective pharmacokinetic study of carbinoxamine in rat plasma by HPLC-MS/MS."New J Chem. 2020 Apr;44(15):5819-5827
cloperastine
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Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: CLOPERASTINE Visit Supplier Webpage Request for quotation
CAS: 3703-76-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
Zouping Mingxing Chemical Co., Ltd.
Product Name: Cloperastine Request for quotation
CAS: 3703-76-2
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987 Click to send a QQ message
Wechat: 13605431940
WhatsApp: 13605431940
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