Name | dichotomitin |
Synonyms | dichotomitin 5,3'-Dihydroxy-4',5'-dimethoxy-6,7-methylenedioxyisoflavone 9-hydroxy-7-(3-hydroxy-4,5-dimethoxyphenyl)-[1,3]dioxolo[4,5-g]chromen-8-one 8H-1,3-Dioxolo[4,5-g][1]benzopyran-8-one,9-hydroxy-7-(3-hydroxy-4,5-dimethoxyphenyl)- |
CAS | 88509-91-5 |
Molecular Formula | C18H14O8 |
Molar Mass | 358.3 |
Density | 1.522±0.06 g/cm3(Predicted) |
Boling Point | 607.3±55.0 °C(Predicted) |
Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
Appearance | White crystalline powder |
pKa | 6.20±0.20(Predicted) |
Storage Condition | 2-8℃ |
Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from shegan. |
Overview | belametin has the effect of reducing the total number of leukocytes and lymphocytes in bronchoalveolar lavage fluid of Cough guinea pigs after infection, it can reduce the content of IL-4 in BALF of model animals and increase the expression level of IFN-γ, suggesting that belametin may exert its anti-inflammatory and antitussive pharmacological effects by regulating the balance of Th1/Th2 in BALF of guinea pigs. |
biological activity | dicotomitin is an isoflavone compound extracted from the rhizome of belamcana chinensis. |
Use | belametin has the functions of promoting blood circulation and detumescence, relieving pain and cough. The main throat, gingival swelling and pain; Cheek; Breast; Stomach pain; Hepatitis; Hepatosplenomegaly; Lung heat cough asthma; Traumatic injury; Paddy field dermatitis. for content determination, identification, pharmacological experiments, activity screening and other pharmacological effects: promoting blood circulation and Detumescence; Relieving pain and cough. Swelling and pain of the main throat and gingiva; Cheek; Breast milk; Stomach pain; Hepatitis; Hepatosplenomegaly; Lung heat, cough and asthma; Traumatic injury |